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Clinical Chemistry 30: 120-121, 1984;
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Clinical Chemistry, Vol 30, 120-121, Copyright © 1984 by American Association for Clinical Chemistry

Salivary estriol concentrations during normal pregnancies, and a comparison with plasma estriol

JJ Evans, AR Wilkinson and DR Aickin

Saliva would have advantages over plasma or urine for monitoring estriol during pregnancy. Specimen collection, after stimulation of flow by citric acid, is non-invasive and simple. We measured concentrations of unconjugated estriol in saliva and compared them with those in plasma in normal pregnancies, and found a good correlation (r = 0.79). In addition, trends of concentrations in saliva and plasma were statistically compared and found to be highly correlated. The variation among individuals in the saliva/plasma concentration ratio suggested that some inter-individual factor(s) may affect this relationship. The normal reference interval for unconjugated estriol concentration in saliva from 20 weeks of gestation to term was established.


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 Microbiol. Mol. Biol. Rev.Home page
H. Marcotte and M. C. Lavoie
Oral Microbial Ecology and the Role of Salivary Immunoglobulin A
Microbiol. Mol. Biol. Rev., March 1, 1998; 62(1): 71 - 109.
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