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Clinical Chemistry 30: 135-137, 1984;
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Clinical Chemistry, Vol 30, 135-137, Copyright © 1984 by American Association for Clinical Chemistry

Simultaneous on-line measurement of blood K+, Ca2+, Na+, and pH with a four-function ChemFET integrated-circuit sensor

A Sibbald, AK Covington and RF Carter

On-line, simultaneous measurement of blood K+, Ca2+, Na+, and pH has been achieved by using a quadruple-function ChemFET (chemical-sensitive field-effect transistor) integrated-circuit sensor. Blood is withdrawn from the subject through an actively heparinized, dual-lumen cannula and passed into a flow-cell containing the sensor, in alternation with a calibration solution. A minicomputer controls the analysis system, logs data, and provides a continuous, graphic display of K+ and pH values.




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Copyright © 1984 by the American Association for Clinical Chemistry.