Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 30: 1611-1615, 1984;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Roboz, J.
Right arrow Articles by Holland, J. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Roboz, J.
Right arrow Articles by Holland, J. F.

Clinical Chemistry, Vol 30, 1611-1615, Copyright © 1984 by American Association for Clinical Chemistry

Determination of polyols in serum by selected ion monitoring

J Roboz, DC Kappatos, J Greaves and JF Holland

We used gas chromatography-chemical ionization mass spectrometry with selected ion monitoring of the (M-59)+ ions to determine polyols (as their peracetyl derivatives) in serum. The internal standard was 2- deoxygalactitol. Mean (and SD) polyol concentrations (mg/L) in 33 normal sera were: erythritol 0.45 (0.14), threitol 0.20 (0.06), adonitol 0.06 (0.02), arabinitol 0.37 (0.12), xylitol 0.05 (0.02), mannitol 0.41 (0.45), galactitol 0.15 (0.11), sorbitol 0.16 (0.11). Arabinitol determined in the same 33 normal sera by trimethylsilylation was 0.39 (0.13) mg/L. In 32 samples from cancer patients with normal creatinine, all polyol concentrations were in the normal range except for seven increased erythritol and one increased threitol concentrations. In all six patients with renal dysfunction we found increased erythritol and arabinitol, and increased threitol and mannitol in four of the six. Initial results showed that only arabinitol concentrations increased in invasive candidiasis.


The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Microbiol. Rev.Home page
S. F. Yeo and B. Wong
Current Status of Nonculture Methods for Diagnosis of Invasive Fungal Infections
Clin. Microbiol. Rev., July 1, 2002; 15(3): 465 - 484.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Microbiol.Home page
S. F. Yeo, Y. Zhang, D. Schafer, S. Campbell, and B. Wong
A Rapid, Automated Enzymatic Fluorometric Assay for Determination of D-Arabinitol in Serum
J. Clin. Microbiol., April 1, 2000; 38(4): 1439 - 1443.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1984 by the American Association for Clinical Chemistry.