Clinical Chemistry
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Clinical Chemistry 30: 1814-1816, 1984;
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Clinical Chemistry, Vol 30, 1814-1816, Copyright © 1984 by American Association for Clinical Chemistry

Combined immunochemical and electrophoretic determinations of proteins in paired serum and cerebrospinal fluid samples

NM Papadopoulos, R Costello, AD Kay, NR Cutler and SI Rapoport

Albumin and immunoglobulin G were simultaneously determined in paired serum and cerebrospinal fluid samples from healthy volunteers. The albumin quotient and the IgG index were calculated to establish normal values. High-resolution electrophoresis was also performed with the same samples and the electrophoretic patterns were correlated with the numerical values to improve the reliability of the test results. Representative examples from abnormal conditions are also shown, to illustrate the increased accuracy and useful applications of this combined analysis in the diagnosis of neurological conditions.




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Copyright © 1984 by the American Association for Clinical Chemistry.