Clinical Chemistry
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Clinical Chemistry 30: 301-303, 1984;
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Clinical Chemistry, Vol 30, 301-303, Copyright © 1984 by American Association for Clinical Chemistry

Liquid-chromatographic evaluation of age-related changes in the urinary excretion of free catecholamines in pediatric patients

TG Rosano

Pediatric patients (to age 18) without neuroblastoma show an age- related decrease in urinary excretion of each of the catecholamines-- epinephrine, norepinephrine, and dopamine--in relation to creatinine excretion. From these data, I have developed reference intervals for pediatric age groups. Application of these ranges to seven patients with neuroblastoma and ganglioneuroblastoma indicated a high clinical sensitivity for the urinary dopamine determination but significant false-negative results for epinephrine and norepinephrine.


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D. S. Ludwig, J. A. Majzoub, A. Al-Zahrani, G. E. Dallal, I. Blanco, and S. B. Roberts
High Glycemic Index Foods, Overeating, and Obesity
Pediatrics, March 1, 1999; 103(3): 26e - 26.
[Abstract] [Full Text]


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