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Clinical Chemistry, Vol 30, 314-315, Copyright © 1984 by American Association for Clinical Chemistry
CR Hamlin and PA Sullivan
Our adaptation of EMIT enzyme immunoassay reagents to the Cobas Bio centrifugal analyzer avoids the decrease in precision at the upper end of the therapeutic range reported in other adaptations. Long-term (12- month) CVs for lidocaine, valproic acid, and tobramycin were 5% or less; for quinidine, acetaminophen, and phenytoin, long-term CVs ranged from 7.2% to 8.6%.
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