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Clinical Chemistry 30: 329-330, 1984;
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Clinical Chemistry, Vol 30, 329-330, Copyright © 1984 by American Association for Clinical Chemistry

A comment on thyrotropin measurement and evaluation

JD Musto, JM Pizzolante and VP Chesarone

There is a need for improvement of thyrotropin measurements in the clinical laboratory, specifically in the lower portion of the normal range. We cite realistic examples of incorrect, misleading data generated with many thyrotropin kits currently in use and propose a practical laboratory protocol to evaluate the performance of a procedure for determining thyrotropin. The protocol integrates medical physiology with analytical measurement.




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Copyright © 1984 by the American Association for Clinical Chemistry.