Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 30: 1225-1227, 1984;
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Erickson, K. A.
Right arrow Articles by Green, P. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Erickson, K. A.
Right arrow Articles by Green, P. J.

Clinical Chemistry, Vol 30, 1225-1227, Copyright © 1984 by American Association for Clinical Chemistry

Intercomparison of seven radioimmunoassay kits and a fluorescence polarization immunoassay kit for digoxin

KA Erickson and PJ Green

Samples from 33 patients being treated with digoxin and three concentrations of control material were analyzed for this drug by use of seven radioimmunoassay (RIA) kits and an automated fluorescence polarization immunoassay (FPIA) system. CVs ranged from 2.4 to 6.4% for the FPIA system and from 4.6 to 7.4% for two RIA methods. In the analysis of between-method variability of RIA kits, CVs ranged from 6.1 to 33.2%. We compared each RIA kit with the other six RIA kits (I), as well as each RIA kit with the FPIA system (II). Correlation coefficients were greater than or equal to 0.96 in all cases. Slopes ranged from 0.82 to 1.20 for comparison I and from 0.86 to 1.01 for comparison II. For the FPIA system, analytical recovery of digoxin ranged from 94 to 104%. For the RIA methods we examined, analytical recoveries ranged from 113 to 135%. Analysis time is shorter and precision is greater for the FPIA system than for the RIA methods.


The following articles in journals at HighWire Press have cited this article:


Home page
 Arch Intern MedHome page
A. D. Mooradian
Discrepancies Between the Calculated Digoxin Clearance and the Serum Digoxin Level in Elderly Patients-Reply
Arch Intern Med, October 1, 1987; 147(10): 1853 - 1853.
[Abstract] [PDF]

Home page
 Arch Intern MedHome page
C. Reider
Discrepancies Between the Calculated Digoxin Clearance and the Serum Digoxin Level in Elderly Patients
Arch Intern Med, October 1, 1987; 147(10): 1852 - 1853.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1984 by the American Association for Clinical Chemistry.