Clinical Chemistry
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Clinical Chemistry 30: 1257-1258, 1984;
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Clinical Chemistry, Vol 30, 1257-1258, Copyright © 1984 by American Association for Clinical Chemistry

Affinity chromatography used in distinguishing alpha-fetoprotein in serum from patients with tumors of hepatic parenchyma and of germ cells

PK Buamah, C Cornell and AW Skillen

We used affinity chromatography on concanavalin A Sepharose to study the serum alpha-fetoprotein of 10 patients with histologically proven germ-cell tumors and 12 patients with primary liver cancer. Less than 50% of the fetoprotein from germ-cell tumors bound to concanavalin A, as compared with more than 80% of the alpha-fetoprotein from primary liver cancers.


The following articles in journals at HighWire Press have cited this article:


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H S Pandha, H S Wasan, K Harrington, and J Waxman
Lesson of the Week: Failure of normalisation of (alpha) fetoprotein concentration after successful treatment of teratoma
BMJ, August 12, 1995; 311(7002): 434 - 435.
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