| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Clinical Chemistry, Vol 30, 1382-1386, Copyright © 1984 by American Association for Clinical Chemistry
HJ Vreman, LK Kwong and DK Stevenson
We examined the sensitive assay for carboxyhemoglobin based on reaction with K3Fe(CN)6 and gas chromatography of the liberated CO. Our improvements included increased baseline stability, shorter analysis time, and simpler standardization. EDTA-containing Vacutainer Tubes (lavender-stoppered) increase the carboxyhemoglobin content of blood stored in them. The carboxyhemoglobin content of blood stored in capillary tubes containing solid heparin and saponin remained stable for two weeks. Using our improved procedures, we measured the carboxyhemoglobin content of blood from adults and neonates collected via venipuncture or heel or fingersticks. We observed no significant difference in carboxyhemoglobin content of blood obtained by venipuncture or heel stick for premature infants, 0.19 +/- 0.04 vs 0.18 +/- 0.03 mL of CO per 100 mL of blood, respectively (mean +/- SD). Nonsmoking adults (n = 19) had CO values (mean +/- SD) of 0.19 +/- 0.03 and 0.17 +/- 0.04 mL per 100 mL of blood, and smoking adults (n = 7) gave CO values of 0.96 +/- 0.49 and 0.91 +/- 0.49 mL/dL, for venipuncture and fingerstick, respectively.
The following articles in journals at HighWire Press have cited this article:
|
|
 |
|
  H. Zhao, R. J. Wong, T. C. Doyle, N. Nayak, H. J. Vreman, C. H. Contag, and D. K. Stevenson Regulation of Maternal and Fetal Hemodynamics by Heme Oxygenase in Mice Biol Reprod, April 1, 2008; 78(4): 744 - 751. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. D. L. Suits, N. Jaffer, and Z. Jia Structure of the Escherichia coli O157:H7 Heme Oxygenase ChuS in Complex with Heme and Enzymatic Inactivation by Mutation of the Heme Coordinating Residue His-193 J. Biol. Chem., December 1, 2006; 281(48): 36776 - 36782. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. D. L. Suits, G. P. Pal, K. Nakatsu, A. Matte, M. Cygler, and Z. Jia Identification of an Escherichia coli O157:H7 heme oxygenase with tandem functional repeats PNAS, November 22, 2005; 102(47): 16955 - 16960. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. van Bel, V. Latour, H. J. Vreman, R. J. Wong, D. K. Stevenson, P. Steendijk, J. Egberts, and T. G. Krediet Is carbon monoxide-mediated cyclic guanosine monophosphate production responsible for low blood pressure in neonatal respiratory distress syndrome? J Appl Physiol, March 1, 2005; 98(3): 1044 - 1049. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M Kaplan, M Muraca, H J Vreman, C Hammerman, M T Vilei, F F Rubaltelli, and D K Stevenson Neonatal bilirubin production-conjugation imbalance: effect of glucose-6-phosphate dehydrogenase deficiency and borderline prematurity Arch. Dis. Child. Fetal Neonatal Ed., March 1, 2005; 90(2): F123 - F127. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. E. Ahlfors and O. Herbsman Unbound Bilirubin in a Term Newborn With Kernicterus Pediatrics, May 1, 2003; 111(5): 1110 - 1112. [Full Text] [PDF]
|
|
|
|
|
|
M. Kaplan, M. Muraca, C. Hammerman, F. F. Rubaltelli, M. T. Vilei, H. J. Vreman, and D. K. Stevenson Imbalance Between Production and Conjugation of Bilirubin: A Fundamental Concept in the Mechanism of Neonatal Jaundice Pediatrics, October 1, 2002; 110(4): e47 - 47. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Thorup, C. L. Jones, S. S. Gross, L. C. Moore, and M. S. Goligorsky Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS Am J Physiol Renal Physiol, December 1, 1999; 277(6): F882 - F889. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. F. Labbe, H. J. Vreman, and D. K. Stevenson Zinc Protoporphyrin: A Metabolite with a Mission Clin. Chem., December 1, 1999; 45(12): 2060 - 2072. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Kaplan, E. Beutler, H. J. Vreman, C. Hammerman, E. Levy-Lahad, P. Renbaum, and D. K. Stevenson Neonatal Hyperbilirubinemia in Glucose-6-Phosphate Dehydrogenase-deficient Heterozygotes Pediatrics, July 1, 1999; 104(1): 68 - 74. [Abstract] [Full Text]
|
|
|
|
|
|
M. Kaplan, H. J Vreman, C. Hammerman, and D. K Stevenson Neonatal bilirubin production, reflected by carboxyhaemoglobin concentrations, in Down's syndrome Arch. Dis. Child. Fetal Neonatal Ed., July 1, 1999; 81(1): 56F - 60. [Abstract] [Full Text]
|
|
|
|
 |
|
 L. M. Baxter, H. J. Vreman, B. Ball, and D. K. Stevenson Recombinant Human Erythropoietin (r-HuEPO) Increases Total Bilirubin Production in Premature Infants Clinical Pediatrics, April 1, 1995; 34(4): 213 - 216. [PDF]
|
|
|
|
|
|
D. K. Stevenson The Carboxyhemoglobin Method for Estimating Bilirubin Production in Neonates: Japanese Studies Clinical Pediatrics, December 1, 1992; 31(12): 708 - 711. [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
