Clinical Chemistry
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Clinical Chemistry 30: 1406-1408, 1984;
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Clinical Chemistry, Vol 30, 1406-1408, Copyright © 1984 by American Association for Clinical Chemistry

Occult causes of hypokalemia

RN Walmsley and GH White

Most causes of hypokalemia are obvious from the clinical picture and the values for plasma electrolytes. In cases with obscure etiology, a pretreatment estimation of urinary potassium and chloride often helps lead the clinician into new and fruitful avenues of clinical investigation. Here we present four cases of hypokalemia in which the pathogenesis was initially enigmatic but was clarified somewhat by the determination of the urinary electrolytes. These simple, inexpensive investigations were initiated by the clinical chemistry laboratory in each case. The results encouraged the physicians to consider further clinical investigations, which led to a definitive diagnosis, before invoking expensive hormonal analyses.


The following articles in journals at HighWire Press have cited this article:


Home page
 Nephrol Dial TransplantHome page
D. Reimann and P. Gross
Chronic, diagnosis-resistant hypokalaemia
Nephrol. Dial. Transplant., December 1, 1999; 14(12): 2957 - 2961.
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Copyright © 1984 by the American Association for Clinical Chemistry.