Clinical Chemistry
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Clinical Chemistry 30: 1473-1476, 1984;
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Clinical Chemistry, Vol 30, 1473-1476, Copyright © 1984 by American Association for Clinical Chemistry

Liquid chromatography in open tubes

MP Maskarinec, MJ Sepaniak, AT Balchunas and JD Vargo

Liquid chromatography in open tubes is evaluated for applicability to clinical analysis. The principal advantages of this technique include high separation power, reduced solvent consumption, and small sample volume requirements. Technology for the production of columns as small as 8 micron (i.d.) is described. Preliminary results are encouraging and, with further development in column and detector technology, the technique should find wide applicability in clinical analysis.




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Copyright © 1984 by the American Association for Clinical Chemistry.