Clinical Chemistry
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Clinical Chemistry 31: 1741-1742, 1985;
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Clinical Chemistry, Vol 31, 1741-1742, Copyright © 1985 by American Association for Clinical Chemistry

Increased activity of creatine kinase isoenzyme MB in a theophylline- intoxicated patient

RH Ng, C Roe, D Funt and BE Statland

A 78-year-old woman had increased activities of creatine kinase (CK; EC 2.7.3.2) and CK-MB isoenzyme in her serum, associated with severe theophylline intoxication. The time course for CK-MB activity was similar to that from an acute myocardial infarction. Clinical findings, however, including electrocardiograms, did not support the diagnosis of myocardial infarction. We suggest caution in interpreting CK-MB results in severe theophylline intoxication.




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Copyright © 1985 by the American Association for Clinical Chemistry.