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Clinical Chemistry 31: 2009-2012, 1985;
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Clinical Chemistry, Vol 31, 2009-2012, Copyright © 1985 by American Association for Clinical Chemistry

Direct-measurement ion-selective electrodes: analytical error in hyponatremia

DC Cowell and PM McGrady

Using two commercial direct ion-selective-electrode sodium and potassium analyzers, we found lower sodium values in cases of hyponatremia as compared with those by flame emission spectrophotometry or indirect ion-selective-electrode analyzers. It is shown that these errors can be eliminated by modifying the calibrant, and that there is a requirement for internationally agreed-upon reference standards for use by manufacturers and laboratory personnel to assess analytical performance of these analyzers.




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Copyright © 1985 by the American Association for Clinical Chemistry.