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Clinical Chemistry 31: 244-246, 1985;
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Clinical Chemistry, Vol 31, 244-246, Copyright © 1985 by American Association for Clinical Chemistry

Relationships between magnesium and protein concentrations in serum

MH Kroll and RJ Elin

We determined concentrations of magnesium, total protein, albumin, and globulin in more than 74 000 serum specimens from patients and noted a direct linear relationship between the concentration of magnesium in serum and the concentrations of total protein, albumin, and globulin in serum. Albumin and magnesium concentrations are linearly related at high and low albumin concentrations; within the reference interval, however, the magnesium concentration is independent of the albumin concentration. Linear regression analysis suggests that 25% of the total serum magnesium is bound to albumin and 8% to globulins.




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Copyright © 1985 by the American Association for Clinical Chemistry.