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Clinical Chemistry 31: 599-600, 1985;
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Clinical Chemistry, Vol 31, 599-600, Copyright © 1985 by American Association for Clinical Chemistry

Measurement of urinary chloride with the Kodak Ektachem 400

MF Melhem, H Seltman and A Sanghvi

Urinary chloride can be measured simply, precisely, and accurately with the Ektachem 400 clinical chemistry analyzer. Because the coated film technique used in this instrument requires the presence of a protein matrix, we added a protein-based calibrator to the urine samples to overcome the low protein concentration in these specimens. Its advantages over a coulometric titration method (Astra analyzer) include the extension of the range of linearity to lower concentrations and the absence of interference from prednisone metabolites in urine. A disadvantage is the negative bias interference of allopurinol.




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Copyright © 1985 by the American Association for Clinical Chemistry.