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Clinical Chemistry, Vol 31, 875-876, Copyright © 1985 by American Association for Clinical Chemistry
C Sheehan and E Carreiro
We report an evaluation of the performance characteristics, accuracy, and sensitivity of five test kits designed to detect human choriogonadotropin (hCG) in urine: "Sensitex" (latex agglutination inhibition), "beta-Neocept" (hemagglutination inhibition), "Duoclone" (direct agglutination), "Tandem-Visual HCG" (enzyme immunoassay), and "Sensichrome" (enzyme immunoassay). For comparison, all specimens and dilutions were also quantified by a radioimmunoassay. The accuracy of these kits was excellent and the manufacturers' stated sensitivity was confirmed. We conclude that the enzyme immunoassay method is the most sensitive procedure for qualitatively detecting hCG.
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