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Clinical Chemistry 32: 2220-2221, 1986;
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Clinical Chemistry, Vol 32, 2220-2221, Copyright © 1986 by American Association for Clinical Chemistry

Multiple myeloma with serum IgM kappa and Bence Jones lambda biclonal gammopathy

MS Graziani and U Lippi

We report a rare finding: IgM kappa and Bence Jones lambda double gammopathy in serum of a 80-year-old man with untreated symptomatic multiple myeloma. The unusual findings are confined to the laboratory studies demonstrating also a Bence Jones lambda proteinuria, high erythrocyte sedimentation rate (113 mm/h), and anemia. The synthesis of the different light chains seems to occur in separate cellular clones.




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