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Clinical Chemistry 32: 521-522, 1986;
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Clinical Chemistry, Vol 32, 521-522, Copyright © 1986 by American Association for Clinical Chemistry

Rapid determination of iron in urine, in the presence of deferoxamine, by inductively coupled plasma emission spectrometry

P Leflon and R Plaquet

Using a spectrometer with an argon plasma source coupled to a high- frequency magnetic field, we developed a direct method for determining iron in urine of patients being treated with deferoxamine. The detection limit for iron was 75 nmol/L; added iron was satisfactorily recovered; and we observed no interference from deferoxamine at its most commonly used concentrations. Values for between-run and within- run precision (CV) was less than 5%. Correlation of results with those obtained with a colorimetric method involving bathophenanthroline was good (r = 0.96).




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Copyright © 1986 by the American Association for Clinical Chemistry.