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Clinical Chemistry 32: 664-668, 1986;
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Clinical Chemistry, Vol 32, 664-668, Copyright © 1986 by American Association for Clinical Chemistry

Simultaneous determination of trace elements in lavage fluids from human bronchial alveoli by energy-dispersive x-ray fluorescence. 2: Determination of abnormal lavage contents and verification of the results

EA Maier, A Dietemann-Molard, F Rastegar, R Heimburger, C Ruch, A Maier, E Roegel and MJ Leroy

We applied energy-dispersive x-ray fluorescence to the determination of abnormally present elements or abnormal concentrations of elements in human broncho-alveolar lavage fluids. The low detection limits and the ability to perform multi-elemental analysis permit one to establish or confirm occupational exposure of workers. We also describe different methods used to check our method and our results. We report examples of abnormal compositions of broncho-alveolar lavages containing W, Ce, La, Nd, I, Fe, or Ni. We discuss the limits of the method for characterizing silicosis or asbestosis.




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Copyright © 1986 by the American Association for Clinical Chemistry.