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Clinical Chemistry 32: 1777-1778, 1986;
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Clinical Chemistry, Vol 32, 1777-1778, Copyright © 1986 by American Association for Clinical Chemistry

Urine discoloration after acetaminophen overdose

PM Clark, JD Clark and T Wheatley

Three patients with acetaminophen overdose were observed to have dark- brown urine at an early stage of their illness. Subsequently, acute anuric renal failure and hepatic dysfunction developed in all three. p- Aminophenol was identified by chromatographic and colorimetric methods in the urine of each case and is thought to be responsible for the discoloration.




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Copyright © 1986 by the American Association for Clinical Chemistry.