Clinical Chemistry
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Clinical Chemistry 33: 2057-2064, 1987;
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Clinical Chemistry, Vol 33, 2057-2064, Copyright © 1987 by American Association for Clinical Chemistry

Trace-element concentrations in human autopsy tissue

TG Aalbers, JP Houtman and B Makkink
Interuniversity Reactor Institute, Delft, The Netherlands.

In this report on trace-element concentrations (As, Ca, Cd, Cl, Co, Cr, Cu, Fe, Hg, K, Mg, Mn, Mo, Na, Ni, Pb, Rb, Sb, Se, Zn) in human heart, liver, kidney, aorta, and rib obtained from 200 autopsied patients, we give special attention to sampling procedure, analysis technique, and various sources of error (autolysis, contamination with blood, and lack of sample homogeneity). We present the concentration data (averages, standard deviations, and ranges) obtained by neutron activation analysis, and we analyze the distribution of the data. The three types of distribution we distinguished are relevant to considerations of the importance of processes of storage of certain elements in specific organs.


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Copyright © 1987 by the American Association for Clinical Chemistry.