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Clinical Chemistry 33: 2278-2280, 1987;
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Clinical Chemistry, Vol 33, 2278-2280, Copyright © 1987 by American Association for Clinical Chemistry

Liquid-chromatographic determination of inosine, xanthine, and hypoxanthine in uremic patients receiving hemodialysis treatment

G Severini and LM Aliberti
Laboratorio Biochimica Clinica, Istituto Superiore di Sanita, Rome, Italy.

We used a liquid-chromatographic method to measure xanthine, hypoxanthine, and inosine in plasma of uremic patients before and after hemodialysis. The concentrations of all three were higher than in normal subjects. After dialysis treatment, the values were significantly lower than before dialysis, but still above normal.




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Copyright © 1987 by the American Association for Clinical Chemistry.