Clinical Chemistry
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Clinical Chemistry 33: 591-593, 1987;
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Clinical Chemistry, Vol 33, 591-593, Copyright © 1987 by American Association for Clinical Chemistry

Lactate and pyruvate electrochemical biosensors for whole blood in extracorporeal experiments with an endocrine artificial pancreas

M Mascini, F Mazzei, D Moscone, G Calabrese and MM Benedetti

Glucose, lactate, and pyruvate can be continuously measured in whole blood by using three extracorporeal electrochemical biosensors. We fixed two newly developed sensors, for lactate and pyruvate, in series with an endocrine artificial pancreas ("Betalike") without affecting its performance. These new sensors for use with whole blood should be able to clarify the fate of the intermediary metabolites of glucose in diabetic patients receiving infusions of drugs or insulin.




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Copyright © 1987 by the American Association for Clinical Chemistry.