| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Clinical Chemistry, Vol 33, 1343-1348, Copyright © 1987 by American Association for Clinical Chemistry
CJ Bojkowski, J Arendt, MC Shih and SP Markey
Comparing a direct radioimmunoassay for 6-sulfatoxymelatonin (aMT6s) with an established gas chromatographic/mass spectrometric method for 6- hydroxymelatonin, we found a good correlation r = 0.94 (P less than 0.001, n = 100). aMT6s was stable, both in urine and plasma samples, without preservative, for at least two years at -20 degrees C and for five days at room temperature. Urinary excretion of aMT6s showed considerable inter-individual differences; however, the aMT6s excretion of any one individual was consistent over a four-day period, as assessed by continuous collection from 18 normal volunteers. Total 24-h urinary excretion of aMT6s was significantly correlated with the area under the curve of the respective profiles for plasma melatonin (r = 0.75, P = 0.0002) and plasma aMT6s (r = 0.70, P = 0.0005) for 22 healthy volunteers. At 24:00 h and 03:00 h, sampling plasma at 30-s intervals provided no evidence for episodic secretion (in short pulses) of either melatonin or aMT6s.
The following articles in journals at HighWire Press have cited this article:
|
|
 |
|
  E. S Schernhammer, D. Feskanich, C. Niu, R. Dopfel, M. D Holmes, and S. E Hankinson Dietary correlates of urinary 6-sulfatoxymelatonin concentrations in the Nurses' Health Study cohorts Am. J. Clinical Nutrition, October 1, 2009; 90(4): 975 - 985. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Lipton, J. T. Megerian, S. V. Kothare, Y-J Cho, T. Shanahan, H. Chart, R. Ferber, L. Adler-Golden, L. E. Cohen, C. A. Czeisler, et al. MELATONIN DEFICIENCY AND DISRUPTED CIRCADIAN RHYTHMS IN PEDIATRIC SURVIVORS OF CRANIOPHARYNGIOMA Neurology, July 28, 2009; 73(4): 323 - 325. [Full Text] [PDF]
|
|
|
|
 |
|
 D. K. Mirick and S. Davis Melatonin as a Biomarker of Circadian Dysregulation Cancer Epidemiol. Biomarkers Prev., December 1, 2008; 17(12): 3306 - 3313. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Arendt, B. Middleton, P. Williams, G. Francis, and C. Luke Sleep and Circadian Phase in a Ship's Crew J Biol Rhythms, June 1, 2006; 21(3): 214 - 221. [Abstract] [PDF]
|
|
|
|
|
|
J. Arendt Melatonin: Characteristics, Concerns, and Prospects J Biol Rhythms, August 1, 2005; 20(4): 291 - 303. [Abstract] [PDF]
|
|
|
|
 |
|
 H. Frisch, F. Waldhauser, T. Waldhor, A. Mullner-Eidenbock, P. Neupane, and K. Schweitzer Increase in 6-Hydroxymelatonin Excretion in Humans during Ascent to High Altitudes J. Clin. Endocrinol. Metab., September 1, 2004; 89(9): 4388 - 4390. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Vijayalaxmi, C. R. Thomas Jr, R. J. Reiter, and T. S. Herman Melatonin: From Basic Research to Cancer Treatment Clinics J. Clin. Oncol., May 15, 2002; 20(10): 2575 - 2601. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Zaouali-Ajina, A. Gharib, G. Durand, N. Gazzah, B. Claustrat, C. Gharib, and N. Sarda Dietary Docosahexaenoic Acid-Enriched Phospholipids Normalize Urinary Melatonin Excretion in Adult (n-3) Polyunsaturated Fatty Acid-Deficient Rats J. Nutr., November 1, 1999; 129(11): 2074 - 2080. [Abstract] [Full Text]
|
|
|
|
 |
|
 A. Sakotnik, P.M. Liebmann, K. Stoschitzky, P. Lercher, K. Schauenstein, W. Klein, and B. Eber Decreased melatonin synthesis in patients with coronary artery disease Eur. Heart J., September 2, 1999; 20(18): 1314 - 1317. [Abstract] [PDF]
|
|
|
|
|
|
A. Kadva, O. Djahanbakhch, J. Monson, W. L. Di, and R. Silman Elevated Nocturnal Melatonin Is a Consequence of Gonadotropin-Releasing Hormone Deficiency in Women with Hypothalamic Amenorrhea J. Clin. Endocrinol. Metab., October 1, 1998; 83(10): 3653 - 3662. [Abstract] [Full Text]
|
|
|
|
 |
|
 G Pillar, A Etzioni, E Shahar, and P Lavie Melatonin treatment in an institutionalised child with psychomotor retardation and an irregular sleep-wake pattern Arch. Dis. Child., July 1, 1998; 79(1): 63 - 64. [Abstract] [Full Text]
|
|
|
|
|
|
S. W. Lockley, D. J. Skene, J. Arendt, H. Tabandeh, A. C. Bird, and R. Defrance Relationship between Melatonin Rhythms and Visual Loss in the Blind J. Clin. Endocrinol. Metab., November 1, 1997; 82(11): 3763 - 3770. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W.-L. Di, A. Kadva, A. Johnston, and R. Silman Variable Bioavailability of Oral Melatonin N. Engl. J. Med., April 3, 1997; 336(14): 1028 - 1029. [Full Text]
|
|
|
|
|
|
S. W. Lockley, D. J. Skene, H. Tabandeh, A. C. Bird, R. Defrance, and J. Arendt Relationship between Napping and Melatonin in the Blind J Biol Rhythms, February 1, 1997; 12(1): 16 - 25. [Abstract] [PDF]
|
|
|
|
 |
|
 A. Wirz-Justice, P. Graw, K. Krauchi, B. Gisin, A. Jochum, J. Arendt, H.-U. Fisch, C. Buddeberg, and W. Poldinger Light Therapy in Seasonal Affective Disorder Is Independent of Time of Day or Circadian Phase Arch Gen Psychiatry, December 1, 1993; 50(12): 929 - 937. [Abstract] [PDF]
|
|
|
|
|
|
O. Tzischinsky, A. Shlitner, and P. Lavie The Association between the Nocturnal Sleep Gate and Nocturnal Onset of Urinary 6-Sulfatoxymelatonin J Biol Rhythms, October 1, 1993; 8(3): 199 - 209. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
