Clinical Chemistry
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Clinical Chemistry 34: 2092-2095, 1988;
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Clinical Chemistry, Vol 34, 2092-2095, Copyright © 1988 by American Association for Clinical Chemistry

Age-related reference values for free amino acids in first morning urine specimens

PR Parvy, JI Bardet, DM Rabier and PP Kamoun
Laboratoire de Biochimie Medicale B, Hopital Necker-Enfants Malades, Paris, France.

We determined age-related reference values for urinary free amino acids (in mmol/mol creatinine) in first morning urine specimens from 360 control subjects who were divided into nine age groups: birth to 1 month, 1-6 months, 6-12 months, 1-2 years, 2-4 years, 4-7 years, 7-10 years, 10-13 years, and older than 13 years. Except for taurine and 3- methylhistidine, the concentration of all the amino acids decreased with increasing age. The use of these results to detect aminoacidopathies and tubulopathies is discussed.


The following articles in journals at HighWire Press have cited this article:


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 Clin. Chem.Home page
U. F.H. Engelke, M. L.F. Liebrand-van Sambeek, J. G.N. de Jong, J. G. Leroy, E. Morava, J. A.M. Smeitink, and R. A. Wevers
N-Acetylated Metabolites in Urine: Proton Nuclear Magnetic Resonance Spectroscopic Study on Patients with Inborn Errors of Metabolism
Clin. Chem., January 1, 2004; 50(1): 58 - 66.
[Abstract] [Full Text] [PDF]

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R. Venta
Year-Long Validation Study and Reference Values for Urinary Amino Acids Using a Reversed-Phase HPLC Method
Clin. Chem., March 1, 2001; 47(3): 575 - 583.
[Abstract] [Full Text] [PDF]


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