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Clinical Chemistry 34: 2120-2122, 1988;
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Clinical Chemistry, Vol 34, 2120-2122, Copyright © 1988 by American Association for Clinical Chemistry

Catecholamine content of human erythrocytes

RJ Altman, CC Smith and J Betteridge
Department of Medicine, University College, London, U.K.

We used high-performance liquid chromatography with electrochemical detection to measure the catecholamine content of human erythrocytes. The ratio of free norepinephrine to epinephrine was three to four times lower than that in plasma and four to seven times lower than that in platelets. This suggests differences in uptake, degradation, or conjugation of norepinephrine and epinephrine by erythrocytes, as compared with plasma and platelets. Erythrocyte free norepinephrine was significantly greater (P less than 0.01) in women than in men.




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Copyright © 1988 by the American Association for Clinical Chemistry.