Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


Clinical Chemistry 34: 715-718, 1988;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Risteli, J.
Right arrow Articles by Risteli, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Risteli, J.
Right arrow Articles by Risteli, L.

Clinical Chemistry, Vol 34, 715-718, Copyright © 1988 by American Association for Clinical Chemistry

Rapid equilibrium radioimmunoassay for the amino-terminal propeptide of human type III procollagen

J Risteli, S Niemi, P Trivedi, O Maentausta, AP Mowat and L Risteli
Collagen Research Unit, Biocenter, Oulu, Finland.

This is an equilibrium-type radioimmunoassay for the amino-terminal propeptide of type III procollagen (PIIINP), which overcomes the problem of nonparallelism between the standard and human serum samples encountered with earlier assays. Proper selection of antiserum and reaction conditions diminishes interference from degradation products of the propeptide in serum. Because a rapid solid-phase-bound second- antibody step is included, the assay takes only 3 h. The intra-assay and the interassay CVs are both about 5%. In infants and children the concentration of PIIINP in serum closely parallels the growth-velocity curve. For 88 presumably healthy adults, the PIIINP concentration was 1.7-4.2 micrograms/L, about a third that measured with the previously available commercial assay. This is because of lack of inhibition by small Col 1 domain-related degradation products.


The following articles in journals at HighWire Press have cited this article:


Home page
Ann Rheum DisHome page
B Mazieres, P Garnero, A Gueguen, M Abbal, L Berdah, M Lequesne, M Nguyen, J-P Salles, E Vignon, and M Dougados
Molecular markers of cartilage breakdown and synovitis at baseline as predictors of structural progression of hip osteoarthritis. The ECHODIAH Cohort
Ann Rheum Dis, March 1, 2006; 65(3): 354 - 359.
[Abstract] [Full Text] [PDF]


Home page
Clin. Chem.Home page
R. Rej
Clinical Chemistry through Clinical Chemistry: A Journal Timeline
Clin. Chem., December 1, 2004; 50(12): 2415 - 2458.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
C. Parkinson, M. Kassem, L. Heickendorff, A. Flyvbjerg, and P. J. Trainer
Pegvisomant-Induced Serum Insulin-Like Growth Factor-I Normalization in Patients with Acromegaly Returns Elevated Markers of Bone Turnover to Normal
J. Clin. Endocrinol. Metab., December 1, 2003; 88(12): 5650 - 5655.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. Velling, J. Risteli, K. Wennerberg, D. F. Mosher, and S. Johansson
Polymerization of Type I and III Collagens Is Dependent On Fibronectin and Enhanced By Integrins alpha 11beta 1 and alpha 2beta 1
J. Biol. Chem., September 27, 2002; 277(40): 37377 - 37381.
[Abstract] [Full Text] [PDF]


Home page
Nephrol Dial TransplantHome page
J. H. Horstrup, M. Gehrmann, B. Schneider, A. Ploger, P. Froese, T. Schirop, D. Kampf, U. Frei, R. Neumann, and K.-U. Eckardt
Elevation of serum and urine levels of TIMP-1 and tenascin in patients with renal disease
Nephrol. Dial. Transplant., June 1, 2002; 17(6): 1005 - 1013.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
C. H. Gravholt, A. L. Lauridsen, K. Brixen, L. Mosekilde, L. Heickendorff, and J. S. Christiansen
Marked Disproportionality in Bone Size and Mineral, and Distinct Abnormalities in Bone Markers and Calcitropic Hormones in Adult Turner Syndrome: A Cross-Sectional Study
J. Clin. Endocrinol. Metab., June 1, 2002; 87(6): 2798 - 2808.
[Abstract] [Full Text] [PDF]


Home page
Toxicol PatholHome page
J. Laitakari and F. Stenback
Collagen Matrix in Development and Progression of Experimentally Induced Respiratory Neoplasms in the Hamster
Toxicol Pathol, August 1, 2001; 29(5): 514 - 527.
[Abstract] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
M. Iwahashi, Y. Muragaki, A. Ooshima, and R. Nakano
Overexpression of Type IV Collagen in Chorionic Villi in Hydatidiform Mole
J. Clin. Endocrinol. Metab., June 1, 2001; 86(6): 2649 - 2652.
[Abstract] [Full Text] [PDF]


Home page
Ann Rheum DisHome page
P Garnero, M Piperno, E Gineyts, S Christgau, P D Delmas, and E Vignon
Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage
Ann Rheum Dis, June 1, 2001; 60(6): 619 - 626.
[Abstract] [Full Text] [PDF]


Home page
Arch. Dis. Child.Home page
C. Heuck, L. Heickendorff, and O. D Wolthers
A randomised controlled trial of short term growth and collagen turnover in asthmatics treated with inhaled formoterol and budesonide
Arch. Dis. Child., October 1, 2000; 83(4): 334 - 339.
[Abstract] [Full Text] [PDF]


Home page
Arch. Dis. Child. Fetal Neonatal Ed.Home page
T Hytinantti, E-M Rutanen, M Turpeinen, R Sorva, and S Andersson
Markers of collagen metabolism and insulin-like growth factor binding protein-1 in term infants
Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2000; 83(1): 17F - 20.
[Abstract] [Full Text]


Home page
Clin. Cancer Res.Home page
M. Santala, M. Simojoki, J. Risteli, L. Risteli, and A. Kauppila
Type I and Type III Collagen Metabolites as Predictors of Clinical Outcome in Epithelial Ovarian Cancer
Clin. Cancer Res., December 1, 1999; 5(12): 4091 - 4096.
[Abstract] [Full Text] [PDF]


Home page
Ann Rheum DisHome page
S Åman, J Risteli, R Luukkainen, L Risteli, M Kauppi, P Nieminen, and M Hakala
The value of synovial fluid analysis in the assessment of knee joint destruction in arthritis in a three year follow up study
Ann Rheum Dis, September 1, 1999; 58(9): 559 - 562.
[Abstract] [Full Text]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
M. K. Bode, M. Mosorin, J. Satta, L. Risteli, T. Juvonen, and J. Risteli
Complete Processing of Type III Collagen in Atherosclerotic Plaques
Arterioscler. Thromb. Vasc. Biol., June 1, 1999; 19(6): 1506 - 1511.
[Abstract] [Full Text] [PDF]


Home page
GutHome page
S Moller, M Hansen, J Hillingso, J-E B Jensen, and J H Henriksen
Elevated carboxy terminal cross linked telopeptide of type I collagen in alcoholic cirrhosis: relation to liver and kidney function and bone metabolism
Gut, March 1, 1999; 44(3): 417 - 423.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Crit. Care Med.Home page
L. LAMMI, L. RYHÄNEN, E. LAKARI, J. RISTELI, P. PÄÄKKÖ, K. KAHLOS, S. LÄHDE, and V. KINNULA
Type III and Type I Procollagen Markers in Fibrosing Alveolitis
Am. J. Respir. Crit. Care Med., March 1, 1999; 159(3): 818 - 823.
[Abstract] [Full Text]


Home page
J. Clin. Endocrinol. Metab.Home page
P. M. Crofton, S. F. Ahmed, J. C. Wade, R. Stephen, M. W. Elmlinger, M. B. Ranke, C. J. H. Kelnar, and W. H. B. Wallace
Effects of Intensive Chemotherapy on Bone and Collagen Turnover and the Growth Hormone Axis in Children with Acute Lymphoblastic Leukemia
J. Clin. Endocrinol. Metab., September 1, 1998; 83(9): 3121 - 3129.
[Abstract] [Full Text]


Home page
CirculationHome page
P. Uusimaa, J. Risteli, M. Niemela, J. Lumme, M. Ikaheimo, A. Jounela, and K. Peuhkurinen
Collagen Scar Formation After Acute Myocardial Infarction : Relationships to Infarct Size, Left Ventricular Function, and Coronary Artery Patency
Circulation, October 21, 1997; 96(8): 2565 - 2572.
[Abstract] [Full Text]


Home page
J. Clin. Endocrinol. Metab.Home page
G. Osella, M. Terzolo, G. Reimondo, A. Piovesan, A. Pia, A. Termine, P. Paccotti, and A. Angeli
Serum Markers of Bone and Collagen Turnover in Patients with Cushing's Syndrome and in Subjects with Adrenal Incidentalomas
J. Clin. Endocrinol. Metab., October 1, 1997; 82(10): 3303 - 3307.
[Abstract] [Full Text] [PDF]


Home page
Clin. Chem.Home page
P. M. Crofton, J. C. Wade, M. R. H. Taylor, and C. V. Holland
Serum concentrations of carboxyl-terminal propeptide of type I procollagen, amino-terminal propeptide of type III procollagen, cross-linked carboxyl-terminal telopeptide of type I collagen, and their interrelationships in schoolchildren
Clin. Chem., September 1, 1997; 43(9): 1577 - 1581.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J. Diez, C. Laviades, G. Mayor, M. J. Gil, and I. Monreal
Increased Serum Concentrations of Procollagen Peptides in Essential Hypertension : Relation to Cardiac Alterations
Circulation, March 1, 1995; 91(5): 1450 - 1456.
[Abstract] [Full Text]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1988 by the American Association for Clinical Chemistry.