Clinical Chemistry
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Clinical Chemistry 34: 744-745, 1988;
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Clinical Chemistry, Vol 34, 744-745, Copyright © 1988 by American Association for Clinical Chemistry

Pre-analytical variation in alanine aminotransferase

SG Ruby, NE Reiber and RE Lonser
Department of Pathology, Hinsdale Hospital, IL 60521.

To determine the effect of pre-analytical variation of alanine aminotransferase in blood specimens with normal activity concentrations of this enzyme, we stored serum and whole blood samples at 4 and 22 degrees C and assayed aliquots of each specimen at intervals up to 72 h. Analysis of variance revealed no statistically significant increase or decrease in activity of the enzyme for up to 72 h in either specimen type, whether stored at room temperature or refrigerated.




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Copyright © 1988 by the American Association for Clinical Chemistry.