Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 34: 1763-1766, 1988;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vaananen, P.
Right arrow Articles by Tenhunen, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vaananen, P.
Right arrow Articles by Tenhunen, R.

Clinical Chemistry, Vol 34, 1763-1766, Copyright © 1988 by American Association for Clinical Chemistry

Rapid immunochemical detection of fecal occult blood by use of a latex- agglutination test

P Vaananen and R Tenhunen
Research Laboratories, Orion Diagnostica, Espoo, Finland.

A novel immunochemical test, "Hemolex," is characterized and compared with three guaiac tests: "Hemoccult" (Smith-Kline, U.S.A.), "Hemofec" (Boehringer Mannheim, F.R.G.), and "Fecatwin Sensitive" (Labsystems, Finland). We tested 191 stool specimens from patients, 144 from healthy persons. The sensitivity of Hemolex was 0.6 mL of blood per 100 g of stool. It reacts with neither animal hemoglobin nor human myoglobin, unlike the guaiac tests, nor does it react with the stool of healthy persons under no dietary restrictions, while the guaiac tests react variably. As a rule, Hemolex is insensitive to bleeding in the upper gastrointestinal tract, unlike the guaiac tests. However, Hemolex seems to be more sensitive to bleeding in the lower gastrointestinal canal than are the other tests, and we show it to be suitable for screening for occult blood originating there. It is unaffected by diet. It is simple to perform, requires no special equipment, and stool specimens, stored in the test diluent, are stable for testing for two weeks.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1988 by the American Association for Clinical Chemistry.