Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 35: 2104-2107, 1989;
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Stanton, N. V.
Right arrow Articles by Field, P. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stanton, N. V.
Right arrow Articles by Field, P. H.

Clinical Chemistry, Vol 35, 2104-2107, Copyright © 1989 by American Association for Clinical Chemistry

Empirically determined lead-poisoning screening cutoff for the Protofluor-Z hematofluorometer

NV Stanton, EW Gunter, PJ Parsons and PH Field
Toxicology Section, Wisconsin State Laboratory of Hygiene, Madison 53706.

A recently introduced hematofluorometer, the "Protofluor-Z" (Helena Laboratories, Beaumont, TX), has several novel features, most notably reporting units expressed as the molar ratio of zinc protoporphyrin (ZPP) to heme, i.e., micromoles of ZPP per mole of heme. We analyzed human blood specimens on the Protofluor-Z and by an ethyl acetate/acetic acid extraction procedure. Data from three laboratories were pooled and used to provide a comparison of the two methods. Results indicate that, with the Protofluor-Z, a value of 70 mumol of ZPP per mole of heme is approximately equivalent to the recommended screening cutoff of 35 micrograms of erythrocyte protoporphyrin per 100 mL of whole blood used in programs for pediatric lead-poisoning prevention. This empirically determined value is slightly lower than either that recommended by the manufacturer or a theoretical cutoff value that was determined mathematically.


The following articles in journals at HighWire Press have cited this article:


Home page
 Arch Pediatr Adolesc MedHome page
P. B. Rolfe, J. F. Marcinak, A. J. Nice, and R. H. Williams
Use of Zinc Protoporphyrin Measured by the Protofluor-Z Hematofluorometer in Screening Children for Elevated Blood Lead Levels
Arch Pediatr Adolesc Med, January 1, 1993; 147(1): 66 - 68.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1989 by the American Association for Clinical Chemistry.