Clinical Chemistry
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Clinical Chemistry 35: 333-334, 1989;
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Clinical Chemistry, Vol 35, 333-334, Copyright © 1989 by American Association for Clinical Chemistry

Factitiously high sodium activities on the Ektachem 400 owing to interferences by high gamma-globulin concentrations

SJ Eastep, PJ Benson, LM Preese and FS Apple
Clinical Laboratories #812, Hennepin County Medical Center, Minneapolis, MN 55415.

Sera from patients with above-normal gamma-globulin concentrations give sodium values as much as 10% higher when measured in the Kodak Ektachem 400 analyzer than results obtained with the Beckman Astra-8 analyzer. Results obtained with the Astra were in agreement with flame photometry. A similar relative bias was observed for potassium measurement in the Ektachem. This discrepancy was corrected when we used a new generation of reference fluid provided by Kodak, which is currently available for general use.




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Copyright © 1989 by the American Association for Clinical Chemistry.