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Clinical Chemistry 35: 828-830, 1989;
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Clinical Chemistry, Vol 35, 828-830, Copyright © 1989 by American Association for Clinical Chemistry

A simplified strategy for testing thyroid function

JM Beaman and JS Woodhead
Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff, U.K.

We assessed a new strategy for thyroid-function testing that involves simultaneous measurement of free thyroxin and thyrotropin, both in singletons, with chemiluminescent assays. Using our current strategy of measuring free thyroxin as a first-line test with selected back-up testing, the results show that, of 810 patients without previous thyroid disease, 445 received back-up tests. Of these, 345 were euthyroid, whereas 63 classified as euthyroid and not selected for further testing in fact had abnormal back-up test results. Evidently the simultaneous measurement of free thyroxin and thyrotropin with the "Magic Lite" technology greatly improves diagnostic efficiency compared with this current strategy.




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Copyright © 1989 by the American Association for Clinical Chemistry.