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Clinical Chemistry 35: 1649-1650, 1989;
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Clinical Chemistry, Vol 35, 1649-1650, Copyright © 1989 by American Association for Clinical Chemistry

Unusually high concentrations of Zn alpha 2-glycoprotein and the lack of alpha 2HS-glycoprotein in human ejaculates

W Burgi, S Simonen, S Baudner and K Schmid
Zentrallaboratorium, Kantonsspital, Aarau, Switzerland.

Ejaculates of 132 nonvasectomized and 129 vasectomized men were assayed for their Zn alpha 2- and alpha 2HS-glycoprotein contents by radial immunodiffusion. The respective mean concentrations of Zn alpha 2- glycoprotein were 319 and 309 mg/L, respectively, but these fluids were devoid of alpha 2HS-glycoprotein. In comparison, the concentration of these two proteins in serum of normal men were 62 and 617 mg/L for Zn alpha 2- and alpha 2HS-glycoprotein, respectively. Because albumin in the ejaculates is 100-fold less concentrated than in serum, the fivefold increase in the concentration of Zn alpha 2-glycoprotein of the ejaculates represents about a 500-fold enrichment of this protein in the ejaculates over the concentration expected by comparison with albumin.


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Copyright © 1989 by the American Association for Clinical Chemistry.