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Clinical Chemistry 36: 1838-1840, 1990;
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Clinical Chemistry, Vol 36, 1838-1840, Copyright © 1990 by American Association for Clinical Chemistry

Anomalous serum thyroxin measurements with the Abbott TDx procedure

S Levine, R Noth, A Loo, IJ Chopra and GG Klee
Clinical Laboratory, VA Medical Center, Martinez, CA 94553.

We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the cause of the problem.


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 Clin. Chem.Home page
N. Despres and A. M. Grant
Antibody interference in thyroid assays: a potential for clinical misinformation
Clin. Chem., March 1, 1998; 44(3): 440 - 454.
[Abstract] [Full Text] [PDF]


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