Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 38: 2454-2457, 1992;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Saitta, M.
Right arrow Articles by Aguzzi, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Saitta, M.
Right arrow Articles by Aguzzi, F.

Clinical Chemistry, Vol 38, 2454-2457, Copyright © 1992 by American Association for Clinical Chemistry

Reference values for immunoglobulin kappa and lambda light chains and the kappa/lambda ratio in children's serum

M Saitta, A Iavarone, N Cappello, MR Bergami, GC Fiorucci and F Aguzzi
Laboratory of Clinical Chemistry and Microbiology, Regina Margherita Children's Hospital, Turin, Italy.

We analyzed 708 serum samples from healthy children and adolescents by immunonephelometry to obtain reference values for the immunoglobulin kappa (kappa) and lambda (lambda) light chains and for their ratio at a time of life when immunoglobulin synthesis is maturing and continually being stimulated. The lambda chain concentration that is to be maintained throughout the child's life is reached very early, just after 1 year, whereas the concentration of the kappa chains, which increases gradually, reflects the concentration of the immunoglobulins as a whole. These reference values may be useful for studying kappa and lambda chains in illnesses involving the immune system in children.


The following articles in journals at HighWire Press have cited this article:


Home page
 J. Exp. Med.Home page
A. V. Popov, X. Zou, J. Xian, I. C. Nicholson, and M. Bruggemann
A Human Immunoglobulin lambda  Locus Is Similarly Well Expressed in Mice and Humans
J. Exp. Med., May 17, 1999; 189(10): 1611 - 1620.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by the American Association for Clinical Chemistry.