Clinical Chemistry
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Clinical Chemistry 38: 358-363, 1992;
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Clinical Chemistry, Vol 38, 358-363, Copyright © 1992 by American Association for Clinical Chemistry

Comparing the power of quality-control rules to detect persistent systematic error

CA Parvin
Department of Pathology, Washington University School of Medicine, St. Louis, MO 63110.

A simulation approach that allows direct estimation of the power of a quality-control rule to detect error that persists until detection is used to compare and evaluate the error detection capabilities of a group of quality-control rules. Two persistent error situations are considered: a constant shift and a linear trend in the quality-control mean. A recently proposed "moving slope" quality-control test for the detection of linear trends is shown to have poor error detection characteristics. A multimean quality-control rule is introduced to illustrate the strategy underlying multirule procedures, which is to increase power without sacrificing response rate. This strategy is shown to provide superior error detection capability when compared with other rules evaluated under both error situations.


The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
J. O. Westgard and B. Stein
Automated Selection of Statistical Quality-Control Procedures to Assure Meeting Clinical or Analytical Quality Requirements
Clin. Chem., February 1, 1997; 43(2): 400 - 403.
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