Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 38: 526-529, 1992;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kanayama, N.
Right arrow Articles by Terao, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kanayama, N.
Right arrow Articles by Terao, T.

Clinical Chemistry, Vol 38, 526-529, Copyright © 1992 by American Association for Clinical Chemistry

Determining zinc coproporphyrin in maternal plasma--a new method for diagnosing amniotic fluid embolism

N Kanayama, T Yamazaki, H Naruse, K Sumimoto, K Horiuchi and T Terao
Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Japan.

We measured the concentration of zinc coproporphyrin I (ZnCP-I), a characteristic component of meconium, in maternal plasma by fluorometry after HPLC. We obtained plasma samples from 89 women: 35 at weeks 10-40 of normal pregnancy, 41 shortly after normal delivery, 4 from patients with amniotic fluid embolism (AFE), and 9 from non-AFE patients with intra- or postpartum shock caused by genital bleeding. The plasma ZnCP- I concentration was 97 (SD 83, range 38-240) nmol/L in the AFE patients, 11 (SD 9.2) nmol/L in the non-AFE patients, 12 (SD 7.9) nmol/L during normal pregnancy, and 26 (SD 10) nmol/L shortly after normal delivery. We suggest that measuring ZnCP-I in maternal plasma by fluorometry on HPLC is a rapid, noninvasive, and sensitive method for diagnosing AFE and propose 35 nmol/L as the cutoff value for the ZnCP-I concentration in maternal plasma for the diagnosis of AFE.


The following articles in journals at HighWire Press have cited this article:


Home page
 Canadian J. AnesthesiaHome page
B. K. Ray, M. C. Vallejo, M. D. Creinin, K. T. Shannon, G. L. Mandell, B. Kaul, and S. Ramanathan
Amniotic fluid embolism with second trimester pregnancy termination: a case report: [Embolie amniotique lors d'une interruption de grossesse au deuxieme trimestre : expose d'un cas]
Can J Anesth, February 1, 2004; 51(2): 139 - 144.
[Abstract] [Full Text] [PDF]

Home page
 Canadian J. AnesthesiaHome page
S. Davies
Amniotic fluid embolus: a review of the literature
Can J Anesth, January 1, 2001; 48(1): 88 - 98.
[Abstract] [Full Text] [PDF]

Home page
 Canadian J. AnesthesiaHome page
M. Bannister and S. Davies
Amniotic fluid embolism
Can J Anesth, April 1, 2000; 47(4): 381 - 381.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by the American Association for Clinical Chemistry.