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Clinical Chemistry 38: 1379-1381, 1992;
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Clinical Chemistry, Vol 38, 1379-1381, Copyright © 1992 by American Association for Clinical Chemistry

Multiple occurrence of macro creatine kinase in one family [clinical conference]

PM Bayer and S Kraus
Department of Clinical Chemistry and Laboratory Medicine, Wilhelminen Hospital, Vienna, Austria.

We measured creatine kinase (CK, EC 2.7.3.2), CK-MB isoenzyme activity and mass concentration, and distribution of CK isoenzymes (by electrophoresis) in serum from five members of one family. The mother and two young children showed CK-IgG complexes in their sera. The concentration of the CK-IgG complexes in the children decreased over time, suggesting that the complex involved maternal IgG and had been transferred across the placenta from the mother to her children.




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Copyright © 1992 by the American Association for Clinical Chemistry.