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Clinical Chemistry 38: 1869-1873, 1992;
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Clinical Chemistry, Vol 38, 1869-1873, Copyright © 1992 by American Association for Clinical Chemistry

Clostebol-positive urine after consumption of contaminated meat

G Debruyckere, R de Sagher and C Van Peteghem
Laboratory of Food Analysis Faculty of Pharmaceutical Sciences, University of Ghent, Belgium.

We examined the relationship between the consumption of meat from animals treated with anabolic steroids and the detection of these steroids in the athletes consuming this meat. We proved that clostebol metabolites (e.g., 4-chloro-delta-4-androstene-3 alpha-ol-17-one) in the urine of one of the volunteers involved in a feeding experiment were due to accidental consumption of meat contaminated with clostebol acetate. When two volunteers consumed meat (100 g) containing either 1 or 0.1 mg of clostebol acetate, the same metabolite was found in their urine.




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Copyright © 1992 by the American Association for Clinical Chemistry.