Clinical Chemistry
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Clinical Chemistry 39: 2191-2198, 1993;
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Clinical Chemistry, Vol 39, 2191-2198, Copyright © 1993 by American Association for Clinical Chemistry

Dietary nutrient intakes and slight albuminuria in people at least 40 years old

PA Metcalf, JR Baker, RK Scragg, E Dryson, AJ Scott and CJ Wild
Department of Community Health, University of Auckland, New Zealand.

We studied the relation between diet and slight albuminuria in 5416 people, ages 40 years and over, who participated in a health screening survey of a local workforce. Degree of albuminuria showed log-linear univariate relations with dietary protein, cholesterol, and sodium intakes, and negative log-linear univariate relations with dietary fiber and polyunsaturated to saturated fat (P/S) ratio. After adjusting for age, gender, and ethnicity, the relative risk (95% confidence interval) for slight albuminuria was significantly increased in people reporting dietary cholesterol consumption > 226 mg/day compared with people reporting consumption < or = 226 mg/day [1.32 (1.02, 1.70)], and significantly reduced in people reporting dietary fiber consumption > 26 g/day compared with people reporting consumption < or = 26 g/day [0.74 (0.58, 0.95)]. There was no significant effect of dietary protein, P/S ratio, or salt intake. We conclude that risk of slight albuminuria is increased by consumption of dietary cholesterol and reduced by consumption of dietary fiber.


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