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Clinical Chemistry 4: 49-61, 1958;
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Clinical Chemistry, Vol 4, 49-61, Copyright © 1958 by the American Association for Clinical Chemistry

Salting-Out of Serum Proteins after the Addition of Known Protein Fractions

E. Pagliardi 1, A. Vitelli 1, and G. Gaidano 1

1 Istituto di Clinica Medica Generale e Terapia Clinica of the University of Turin, Italy.

Salting-out of sera to which known protein fractions had been added was performed, and parallel determinations were performed on the unaltered serum in every case. Two types of phenomena were observed: the added fraction apparently always precipitates in its characteristic range, and the addition of proteins sometimes did not modify the precipitation of the serum proteins, but in other cases determined important changes of the precipitation diagram. The study of these changes proved the occurrence of processes of interaction between the various protein fractions of the sera.

Submitted on July 9, 1957






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Copyright © 1958 by the American Association for Clinical Chemistry.