Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 42: 942-946, 1996;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ma, Z.
Right arrow Articles by Landt, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ma, Z.
Right arrow Articles by Landt, M.

Clinical Chemistry, Vol 42, 942-946, Copyright © 1996 by American Association for Clinical Chemistry

Radioimmunoassay of leptin in human plasma

Z Ma, RL Gingerich, JV Santiago, S Klein, CH Smith and M Landt
Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.

Recent studies suggest that leptin, the ob gene product absent in ob/ob mice, is a negative regulator of adiposity. We developed an RIA to measure human leptin in plasma or serum. The minimum detectable concentration by the assay is 0.5 microg/L leptin and the limit of linearity is 100 microg/L. Recovery of leptin added to serum was 99- 104% over by the linear range of the assay. The RIA agreed reasonably well with rough quantification by Western blot (RIA = 0.90 blot + 3.7 microg/L, Sy/x = 10.9 microg/L). CVs within- and between-run ranged from 3.4% to 8.3% and from 3.6% to 6.2%, respectively. Variation in plasma leptin concentrations in specimens collected on consecutive mornings was large (CVs of 10.9% and 22.5%). After an overnight fast, leptin concentrations were similar to those 1-2 h after 1-2 meals. Plasma leptin concentrations in specimens from 83 lean and obese adults correlated directly with body mass index (BMI; kg/m2): r = 0.72, P <0.001. Correlations were significantly improved by separating results by gender (men r = 0.84, women r = 0.87; p <0.001). The increase in leptin concentrations with increasing BMI was greater in women than in men (slope 2.53 vs 0.97 microg/L per unit BMI, respectively). Leptin concentrations determined in lean subjects (BMI between 18 and 25) were higher in women (7.36 +/- 3.73 microg/L) than in men (3.84 +/- 1.79 microg/L) (P <0.001). Plasma leptin varied little with age and no significant difference was observed between whites and blacks. We conclude that: (a) plasma leptin concentrations are accurately and precisely measured by this new RIA; (b) leptin concentrations vary little due to short-term fasting, age, or race; but (c) plasma leptin concentrations are gender specific.


The following articles in journals at HighWire Press have cited this article:


Home page
 J. Clin. Endocrinol. Metab.Home page
J. Roper, F. Francois, P. L. Shue, M. S. Mourad, Z. Pei, A. Z. Olivares de Perez, G. I. Perez-Perez, C.-H. Tseng, and M. J. Blaser
Leptin and Ghrelin in Relation to Helicobacter pylori Status in Adult Males
J. Clin. Endocrinol. Metab., June 1, 2008; 93(6): 2350 - 2357.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
B.-S. Youn, N. Kloting, J. Kratzsch, N. Lee, J. W. Park, E.-S. Song, K. Ruschke, A. Oberbach, M. Fasshauer, M. Stumvoll, et al.
Serum Vaspin Concentrations in Human Obesity and Type 2 Diabetes
Diabetes, February 1, 2008; 57(2): 372 - 377.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
J. Seeger, M. Ziegelmeier, A. Bachmann, U. Lossner, J. Kratzsch, M. Bluher, M. Stumvoll, and M. Fasshauer
Serum Levels of the Adipokine Vaspin in Relation to Metabolic and Renal Parameters
J. Clin. Endocrinol. Metab., January 1, 2008; 93(1): 247 - 251.
[Abstract] [Full Text] [PDF]

Home page
 Schizophr BullHome page
O. Sentissi, J. Epelbaum, J.-P. Olie, and M.-F. Poirier
Leptin and Ghrelin Levels in Patients With Schizophrenia During Different Antipsychotics Treatment: A Review
Schizophr Bull, December 28, 2007; (2007) sbm141v1.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
C. E Ruhl, T. B Harris, J. Ding, B. H Goodpaster, A. M Kanaya, S. B Kritchevsky, E. M Simonsick, F. A Tylavsky, J. E Everhart, and for the Health ABC Study
Body mass index and serum leptin concentration independently estimate percentage body fat in older adults
Am. J. Clinical Nutrition, April 1, 2007; 85(4): 1121 - 1126.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
C. Shibao, A. Gamboa, A. Diedrich, A. C. Ertl, K. Y. Chen, D. W. Byrne, G. Farley, S. Y. Paranjape, S. N. Davis, and I. Biaggioni
Autonomic Contribution to Blood Pressure and Metabolism in Obesity
Hypertension, January 1, 2007; 49(1): 27 - 33.
[Abstract] [Full Text] [PDF]

Home page
 CarcinogenesisHome page
K.-H. Lee, H. Bartsch, J. Nair, D.-H. Yoo, Y.-C. Hong, S.-H. Cho, and D. Kang
Effect of short-term fasting on urinary excretion of primary lipid peroxidation products and on markers of oxidative DNA damage in healthy women
Carcinogenesis, July 1, 2006; 27(7): 1398 - 1403.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
I. Cho, M. J. Blaser, F. Francois, J. P. Mathew, X. Y. Ye, J. D. Goldberg, and E. J. Bini
Helicobacter pylori and Overweight Status in the United States: Data from the Third National Health and Nutrition Examination Survey
Am. J. Epidemiol., September 15, 2005; 162(6): 579 - 584.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
S. Dagogo-Jack, G. Tykodi, and I. Umamaheswaran
Inhibition of Cortisol Biosynthesis Decreases Circulating Leptin Levels in Obese Humans
J. Clin. Endocrinol. Metab., September 1, 2005; 90(9): 5333 - 5335.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
G. Grassi, A. Facchini, F. Q. Trevano, R. Dell'Oro, F. Arenare, F. Tana, G. Bolla, A. Monzani, M. Robuschi, and G. Mancia
Obstructive Sleep Apnea-Dependent and -Independent Adrenergic Activation in Obesity
Hypertension, August 1, 2005; 46(2): 321 - 325.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
E. D. Javor, E. K. Cochran, C. Musso, J. R. Young, A. M. DePaoli, and P. Gorden
Long-Term Efficacy of Leptin Replacement in Patients With Generalized Lipodystrophy
Diabetes, July 1, 2005; 54(7): 1994 - 2002.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
J. Tong, W. Y. Fujimoto, S. E. Kahn, D. S. Weigle, M. J. McNeely, D. L. Leonetti, J. B. Shofer, and E. J. Boyko
Insulin, C-Peptide, and Leptin Concentrations Predict Increased Visceral Adiposity at 5- and 10-Year Follow-Ups in Nondiabetic Japanese Americans
Diabetes, April 1, 2005; 54(4): 985 - 990.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Chem.Home page
R. Rej
Clinical Chemistry through Clinical Chemistry: A Journal Timeline
Clin. Chem., December 1, 2004; 50(12): 2415 - 2458.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
C. E Ruhl, J. E Everhart, J. Ding, B. H Goodpaster, A. M Kanaya, E. M Simonsick, F. A Tylavsky, and T. B Harris
Serum leptin concentrations and body adipose measures in older black and white adults
Am. J. Clinical Nutrition, September 1, 2004; 80(3): 576 - 583.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
E. D. Javor, S. A. Moran, J. R. Young, E. K. Cochran, A. M. DePaoli, E. A. Oral, M. A. Turman, P. R. Blackett, D. B. Savage, S. O'Rahilly, et al.
Proteinuric Nephropathy in Acquired and Congenital Generalized Lipodystrophy: Baseline Characteristics and Course during Recombinant Leptin Therapy
J. Clin. Endocrinol. Metab., July 1, 2004; 89(7): 3199 - 3207.
[Abstract] [Full Text] [PDF]

Home page
 Alcohol AlcoholHome page
J. CALISSENDORFF, K. BRISMAR, and S. ROJDMARK
IS DECREASED LEPTIN SECRETION AFTER ALCOHOL INGESTION CATECHOLAMINE-MEDIATED?
Alcohol Alcohol., July 1, 2004; 39(4): 281 - 286.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
S. J. Murdoch, S. E. Kahn, J. J. Albers, J. D. Brunzell, and J. Q. Purnell
PLTP activity decreases with weight loss: changes in PLTP are associated with changes in subcutaneous fat and FFA but not IAF or insulin sensitivity
J. Lipid Res., September 1, 2003; 44(9): 1705 - 1712.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
G. R. Hynes, J. Heshka, K. Chadee, and P. J. Jones
Effects of dietary fat type and energy restriction on adipose tissue fatty acid composition and leptin production in rats
J. Lipid Res., May 1, 2003; 44(5): 893 - 901.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
M. Faraj, P. J. Havel, S. Phelis, D. Blank, A. D. Sniderman, and K. Cianflone
Plasma Acylation-Stimulating Protein, Adiponectin, Leptin, and Ghrelin before and after Weight Loss Induced by Gastric Bypass Surgery in Morbidly Obese Subjects
J. Clin. Endocrinol. Metab., April 1, 2003; 88(4): 1594 - 1602.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
N. Anim-Nyame, J. Gamble, S. R. Sooranna, M. R. Johnson, and P. J. Steer
Microvascular permeability is related to circulating levels of tumour necrosis factor-{alpha} in pre-eclampsia
Cardiovasc Res, April 1, 2003; 58(1): 162 - 169.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
A. Raben, L. Agerholm-Larsen, A. Flint, J. J Holst, and A. Astrup
Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake
Am. J. Clinical Nutrition, January 1, 2003; 77(1): 91 - 100.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
P. O. Iversen, C. A. Drevon, and J. E. Reseland
Prevention of leptin binding to its receptor suppresses rat leukemic cell growth by inhibiting angiogenesis
Blood, December 1, 2002; 100(12): 4123 - 4128.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child.Home page
S E Moore, G Morgan, A C Collinson, J A Swain, M A O'Connell, and A M Prentice
Leptin, malnutrition, and immune response in rural Gambian children
Arch. Dis. Child., September 1, 2002; 87(3): 192 - 197.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
C. A. Matson, D. F. Reid, and R. C. Ritter
Daily CCK injection enhances reduction of body weight by chronic intracerebroventricular leptin infusion
Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2002; 282(5): R1368 - R1373.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
M. Cnop, M. J. Landchild, J. Vidal, P. J. Havel, N. G. Knowles, D. R. Carr, F. Wang, R. L. Hull, E. J. Boyko, B. M. Retzlaff, et al.
The Concurrent Accumulation of Intra-Abdominal and Subcutaneous Fat Explains the Association Between Insulin Resistance and Plasma Leptin Concentrations : Distinct Metabolic Effects of Two Fat Compartments
Diabetes, April 1, 2002; 51(4): 1005 - 1015.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
R. Arya, J. Blangero, K. Williams, L. Almasy, T. D. Dyer, R. J. Leach, P. O'Connell, M. P. Stern, and R. Duggirala
Factors of Insulin Resistance Syndrome-Related Phenotypes Are Linked to Genetic Locations on Chromosomes 6 and 7 in Nondiabetic Mexican-Americans
Diabetes, March 1, 2002; 51(3): 841 - 847.
[Abstract] [Full Text] [PDF]

Home page
 PsychosomaticsHome page
K. Melkersson and A.-L. Hulting
Recovery From New-Onset Diabetes in a Schizophrenic Man After Withdrawal of Olanzapine
Psychosomatics, February 1, 2002; 43(1): 67 - 70.
[Full Text]

Home page
 DiabetesHome page
T. P. Ciaraldi, A. P.S. Kong, N. V. Chu, D. D. Kim, S. Baxi, M. Loviscach, R. Plodkowski, R. Reitz, M. Caulfield, S. Mudaliar, et al.
Regulation of Glucose Transport and Insulin Signaling by Troglitazone or Metformin in Adipose Tissue of Type 2 Diabetic Subjects
Diabetes, January 1, 2002; 51(1): 30 - 36.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
C. E Ruhl and J. E Everhart
Leptin concentrations in the United States: relations with demographic and anthropometric measures
Am. J. Clinical Nutrition, September 1, 2001; 74(3): 295 - 301.
[Abstract] [Full Text]

Home page
 GutHome page
T Azuma, H Suto, Y Ito, M Ohtani, M Dojo, M Kuriyama, and T Kato
Gastric leptin and Helicobacter pylori infection
Gut, September 1, 2001; 49(3): 324 - 329.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
T K Hytinantti, M Juntunen, H A Koistinen, V A Koivisto, S-L Karonen, and S Andersson
Postnatal changes in concentrations of free and bound leptin
Arch. Dis. Child. Fetal Neonatal Ed., September 1, 2001; 85(2): F123 - 126.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. S. Fisher, R. E. Van Pelt, O. Zinder, M. Landt, and W. M. Kohrt
Acute exercise effect on postabsorptive serum leptin
J Appl Physiol, August 1, 2001; 91(2): 680 - 686.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
M. Landt, J. F. Horowitz, S. W. Coppack, and S. Klein
Effect of Short-Term Fasting on Free and Bound Leptin Concentrations in Lean and Obese Women
J. Clin. Endocrinol. Metab., August 1, 2001; 86(8): 3768 - 3771.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
J. D. Veldhuis, S. M. Pincus, M. C. Garcia-Rudaz, M. G. Ropelato, M. E. Escobar, and M. Barontini
Disruption of the Synchronous Secretion of Leptin, LH, and Ovarian Androgens in Nonobese Adolescents with the Polycystic Ovarian Syndrome
J. Clin. Endocrinol. Metab., August 1, 2001; 86(8): 3772 - 3778.
[Abstract] [Full Text] [PDF]

Home page
 JNCI J Natl Cancer InstHome page
A. W. Hsing, S. Chua Jr, Y.-T. Gao, E. Gentzschein, L. Chang, J. Deng, and F. Z. Stanczyk
Prostate Cancer Risk and Serum Levels of Insulin and Leptin: a Population-Based Study
J Natl Cancer Inst, May 16, 2001; 93(10): 783 - 789.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
J. E. Reseland, F. Haugen, K. Hollung, K. Solvoll, B. Halvorsen, I. R. Brude, M. S. Nenseter, E. N. Christiansen, and C. A. Drevon
Reduction of leptin gene expression by dietary polyunsaturated fatty acids
J. Lipid Res., May 1, 2001; 42(5): 743 - 750.
[Abstract] [Full Text]

Home page
 J. Clin. Endocrinol. Metab.Home page
F. Callies, M. Fassnacht, J. C. van Vlijmen, I. Koehler, D. Huebler, M. J. Seibel, W. Arlt, and B. Allolio
Dehydroepiandrosterone Replacement in Women with Adrenal Insufficiency: Effects on Body Composition, Serum Leptin, Bone Turnover, and Exercise Capacity
J. Clin. Endocrinol. Metab., May 1, 2001; 86(5): 1968 - 1972.
[Abstract] [Full Text]

Home page
 Hum ReprodHome page
L. Unkila-Kallio, S. Andersson, H.A. Koistinen, S.-L. Karonen, O. Ylikorkala, and A. Tiitinen
Leptin during assisted reproductive cycles: the effect of ovarian stimulation and of very early pregnancy
Hum. Reprod., April 1, 2001; 16(4): 657 - 662.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
J. F Horowitz, S. W Coppack, and S. Klein
Whole-body and adipose tissue glucose metabolism in response to short-term fasting in lean and obese women
Am. J. Clinical Nutrition, March 1, 2001; 73(3): 517 - 522.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
J. E Reseland, S. A Anderssen, K. Solvoll, I. Hjermann, P. Urdal, I. Holme, and C. A Drevon
Effect of long-term changes in diet and exercise on plasma leptin concentrations
Am. J. Clinical Nutrition, February 1, 2001; 73(2): 240 - 245.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
T. O Scholl, T P. Stein, and W. K Smith
Leptin and maternal growth during adolescent pregnancy
Am. J. Clinical Nutrition, December 1, 2000; 72(6): 1542 - 1547.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
N. Anim-Nyame, C. Domoney, N. Panay, J. Jones, J. Alaghband-Zadeh, and J.W.W. Studd
Plasma leptin concentrations are increased in women with premenstrual syndrome
Hum. Reprod., November 1, 2000; 15(11): 2329 - 2332.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
R. F. Gariano, A. K. Nath, D. J. D’Amico, T. Lee, and M. R. Sierra–Honigmann
Elevation of Vitreous Leptin in Diabetic Retinopathy and Retinal Detachment
Invest. Ophthalmol. Vis. Sci., October 1, 2000; 41(11): 3576 - 3581.
[Abstract] [Full Text]

Home page
 ChestHome page
M. S. M. Ip, K. S. L. Lam, C.-m. Ho, K. W. T. Tsang, and W.-k. Lam
Serum Leptin and Vascular Risk Factors in Obstructive Sleep Apnea
Chest, September 1, 2000; 118(3): 580 - 586.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
N. Anim-Nyame, S.R. Sooranna, P.J. Steer, and M.R. Johnson
Longitudinal analysis of maternal plasma leptin concentrations during normal pregnancy and pre-eclampsia
Hum. Reprod., September 1, 2000; 15(9): 2033 - 2036.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
B. Lonnerdal and P. J Havel
Serum leptin concentrations in infants: effects of diet, sex, and adiposity
Am. J. Clinical Nutrition, August 1, 2000; 72(2): 484 - 489.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. S. Greiwe, J. O. Holloszy, and C. F. Semenkovich
Exercise induces lipoprotein lipase and GLUT-4 protein in muscle independent of adrenergic-receptor signaling
J Appl Physiol, July 1, 2000; 89(1): 176 - 181.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
T. Hytinantti, H. A Koistinen, V. A Koivisto, S.-L. Karonen, E.-M. Rutanen, S. Andersson;, A. BEREZIN, and M. MELO
Increased leptin concentration in preterm infants of pre-eclamptic mothers
Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2000; 83(1): 13F - 16.
[Abstract] [Full Text]

Home page
 Clin. Chem.Home page
M. Landt, C. A. Parvin, and M. Wong
Leptin in Cerebrospinal Fluid from Children: Correlation with Plasma Leptin, Sexual Dimorphism, and Lack of Protein Binding
Clin. Chem., June 1, 2000; 46(6): 854 - 858.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
A. M. Rice, J. N. Fain, and S. A. Rivkees
A1 Adenosine Receptor Activation Increases Adipocyte Leptin Secretion
Endocrinology, April 1, 2000; 141(4): 1442 - 1445.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Chem.Home page
M. Landt
Leptin Binding and Binding Capacity in Serum
Clin. Chem., March 1, 2000; 46(3): 379 - 384.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
M. M. Hagan, P. J. Havel, R. J. Seeley, S. C. Woods, N. N. Ekhator, D. G. Baker, K. K. Hill, M. D. Wortman, A. H. Miller, R. L. Gingerich, et al.
Cerebrospinal Fluid and Plasma Leptin Measurements: Covariability with Dopamine and Cortisol in Fasting Humans
J. Clin. Endocrinol. Metab., October 1, 1999; 84(10): 3579 - 3585.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
J. S. Fisher, R. C. Hickner, S. B. Racette, E. F. Binder, M. Landt, and W. M. Kohrt
Leptin Response to Insulin in Humans Is Related to the Lipolytic State of Abdominal Subcutaneous Fat
J. Clin. Endocrinol. Metab., October 1, 1999; 84(10): 3726 - 3731.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
J. E. Hixson, L. Almasy, S. Cole, S. Birnbaum, B. D. Mitchell, M. C. Mahaney, M. P. Stern, J. W. MacCluer, J. Blangero, and A. G. Comuzzie
Normal Variation in Leptin Levels Is Associated with Polymorphisms in the Proopiomelanocortin Gene, POMC
J. Clin. Endocrinol. Metab., September 1, 1999; 84(9): 3187 - 3191.
[Abstract] [Full Text]

Home page
 PediatricsHome page
B. Tarquini, R. Tarquini, F. Perfetto, G. Cornélissen, and F. Halberg
Genetic and Environmental Influences on Human Cord Blood Leptin Concentration
Pediatrics, May 1, 1999; 103(5): 998 - 1006.
[Abstract] [Full Text]

Home page
 EndocrinologyHome page
F. Machinal, M.-N. Dieudonne, M.-C. Leneveu, R. Pecquery, and Y. Giudicelli
In Vivo and in Vitro ob Gene Expression and Leptin Secretion in Rat Adipocytes: Evidence for a Regional Specific Regulation by Sex Steroid Hormones
Endocrinology, April 1, 1999; 140(4): 1567 - 1574.
[Abstract] [Full Text]

Home page
 Am. J. Respir. Crit. Care Med.Home page
N. TAKABATAKE, H. NAKAMURA, S. ABE, T. HINO, H. SAITO, H. YUKI, S. KATO, and H. TOMOIKE
Circulating Leptin in Patients with Chronic Obstructive Pulmonary Disease
Am. J. Respir. Crit. Care Med., April 1, 1999; 159(4): 1215 - 1219.
[Abstract] [Full Text] [PDF]

Home page
 Reproductive SciencesHome page
M. Shaarawy and S. Y. El-Mallah
Leptin and Gestational Weight Gain: Relation of Maternal and Cord Blood Leptin to Birth Weight
Reproductive Sciences, March 1, 1999; 6(2): 70 - 73.
[Abstract] [PDF]

Home page
 BloodHome page
M. Konopleva, A. Mikhail, Z. Estrov, S. Zhao, D. Harris, G. Sanchez-Williams, S. M. Kornblau, J. Dong, K.-O. Kliche, S. Jiang, et al.
Expression and Function of Leptin Receptor Isoforms in Myeloid Leukemia and Myelodysplastic Syndromes: Proliferative and Anti-Apoptotic Activities
Blood, March 1, 1999; 93(5): 1668 - 1676.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
M. D Jensen, N. Moller, K Sreekumaran Nair, P. Eisenberg, M. Landt, and S. Klein
Regional leptin kinetics