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Articles |
Departments of
1
Pediatrics and
2
Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287.
3
The National Center for Health Statistics, Centers for
Disease Control and Prevention, Hyattsville, MD 20872.
a Address for correspondence: Blalock 1379, The Johns Hopkins Hospital, 600 North Wolfe St., Baltimore, MD 21287. Fax 410-955-3247.
Serum apolipoproteins (apo) B and AI were measured in a probability
sample of the noninstitutionalized US civilian population, ages 
4
years, which included non-Hispanic whites, non-Hispanic blacks, and
Mexican-Americans. Apo B concentrations were the same in males and
females, lower in black males than in other males, low in childhood
(~0.80 g/L) and increasing to ~1.2 g/L in adults, and higher in
younger women on hormones. Apo AI was higher in females than males,
higher in blacks than in others, remained constant from childhood to
adulthood (~1.35 g/L) in males, but increased with age (~1.30 g/L
to ~1.55 g/L) in females, and was higher in women taking hormones.
These are the first national probability estimates of apo B and apo AI
in the US and are referable to the WHO-IFCC First International
Reference Materials for apo AI and B.
The following articles in journals at HighWire Press have cited this article:
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  C. J. Chantry, M. D. Hughes, C. Alvero, J. S. Cervia, W. A. Meyer III, J. Hodge, P. Borum, J. Moye Jr, and for the PACTG 1010 Team Lipid and Glucose Alterations in HIV-Infected Children Beginning or Changing Antiretroviral Therapy Pediatrics, July 1, 2008; 122(1): e129 - e138. [Abstract] [Full Text] [PDF]
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 D. Gozal, O. S. Capdevila, and L. Kheirandish-Gozal Metabolic Alterations and Systemic Inflammation in Obstructive Sleep Apnea among Nonobese and Obese Prepubertal Children Am. J. Respir. Crit. Care Med., May 15, 2008; 177(10): 1142 - 1149. [Abstract] [Full Text] [PDF]
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 R. Sherva, P. Yue, G. Schonfeld, and R. J. Neuman Evidence for a quantitative trait locus affecting low levels of apolipoprotein B and low density lipoprotein on chromosome 10 in Caucasian families J. Lipid Res., December 1, 2007; 48(12): 2632 - 2639. [Abstract] [Full Text] [PDF]
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 J. S. Saczynski, L. White, R. L. Peila, B. L. Rodriguez, and L. J. Launer The Relation between Apolipoprotein A-I and Dementia: The Honolulu-Asia Aging Study Am. J. Epidemiol., May 1, 2007; 165(9): 985 - 992. [Abstract] [Full Text] [PDF]
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 L. E. Moore, E. T. Fung, M. McGuire, C. C. Rabkin, A. Molinaro, Z. Wang, F. Zhang, J. Wang, C. Yip, X.-Y. Meng, et al. Evaluation of apolipoprotein A1 and posttranslationally modified forms of transthyretin as biomarkers for ovarian cancer detection in an independent study population. Cancer Epidemiol. Biomarkers Prev., September 1, 2006; 15(9): 1641 - 1646. [Abstract] [Full Text] [PDF]
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 M. A. Denke Weighing in Before the Fight: Low-Density Lipoprotein Cholesterol and Non-High-Density Lipoprotein Cholesterol Versus Apolipoprotein B as the Best Predictor for Coronary Heart Disease and the Best Measure of Therapy Circulation, November 29, 2005; 112(22): 3368 - 3370. [Full Text] [PDF]
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 D. J. Blom, F. H. O'Neill, and A. D. Marais Screening for Dysbetalipoproteinemia by Plasma Cholesterol and Apolipoprotein B Concentrations Clin. Chem., May 1, 2005; 51(5): 904 - 907. [Full Text] [PDF]
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N. Sattar, K. Williams, A. D. Sniderman, R. D'Agostino Jr, and S. M. Haffner Comparison of the Associations of Apolipoprotein B and Non-High-Density Lipoprotein Cholesterol With Other Cardiovascular Risk Factors in Patients With the Metabolic Syndrome in the Insulin Resistance Atherosclerosis Study Circulation, October 26, 2004; 110(17): 2687 - 2693. [Abstract] [Full Text] [PDF]
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 Z. Zhang, R. C. Bast Jr., Y. Yu, J. Li, L. J. Sokoll, A. J. Rai, J. M. Rosenzweig, B. Cameron, Y. Y. Wang, X.-Y. Meng, et al. Three Biomarkers Identified from Serum Proteomic Analysis for the Detection of Early Stage Ovarian Cancer Cancer Res., August 15, 2004; 64(16): 5882 - 5890. [Abstract] [Full Text] [PDF]
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 M. C. Carr and J. D. Brunzell Abdominal Obesity and Dyslipidemia in the Metabolic Syndrome: Importance of Type 2 Diabetes and Familial Combined Hyperlipidemia in Coronary Artery Disease Risk J. Clin. Endocrinol. Metab., June 1, 2004; 89(6): 2601 - 2607. [Abstract] [Full Text] [PDF]
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M. Averina, O. Nilssen, T. Brenn, J. Brox, V. L. Arkhipovsky, and A. G. Kalinin Factors behind the Increase in Cardiovascular Mortality in Russia: Apolipoprotein AI and B Distribution in the Arkhangelsk Study 2000 Clin. Chem., February 1, 2004; 50(2): 346 - 354. [Abstract] [Full Text] [PDF]
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 A. M. Wagner, A. Perez, E. Zapico, and J. Ordonez-Llanos Non-HDL Cholesterol and Apolipoprotein B in the Dyslipidemic Classification of Type 2 Diabetic Patients Diabetes Care, July 1, 2003; 26(7): 2048 - 2051. [Abstract] [Full Text] [PDF]
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P. O. Kwiterovich Jr., S. C. Chen, D. G. Virgil, A. Schweitzer, D. R. Arnold, and L. E. Kratz Response of obligate heterozygotes for phytosterolemia to a low-fat diet and to a plant sterol ester dietary challenge J. Lipid Res., June 1, 2003; 44(6): 1143 - 1155. [Abstract] [Full Text] [PDF]
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W. J. Shih, P. S. Bachorik, J. A. Haga, G. L. Myers, and E. A. Stein Estimating the Long-Term Effects of Storage at -70 {degrees}C on Cholesterol, Triglyceride, and HDL-Cholesterol Measurements in Stored Sera Clin. Chem., March 1, 2000; 46(3): 351 - 364. [Abstract] [Full Text] [PDF]
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I. Jungner, S. M. Marcovina, G. Walldius, I. Holme, W. Kolar, and E. Steiner Apolipoprotein B and A-I values in 147 576 Swedish males and females, standardized according to the World Health Organization–International Federation of Clinical Chemistry First International Reference Materials Clin. Chem., August 1, 1998; 44(8): 1641 - 1649. [Abstract] [Full Text] [PDF]
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