Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 43: 1056-1065, 1997;
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (18)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Smith, S. M.
Right arrow Articles by Lane, H. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Smith, S. M.
Right arrow Articles by Lane, H. W.
Related Collections
Right arrow General Clinical Chemistry
(Clinical Chemistry. 1997;43:1056-1065.)
© 1997 American Association for Clinical Chemistry, Inc.

Articles

Assessment of a portable clinical blood analyzer during space flight

Scott M. Smith1,a, Janis E. Davis-Street3, Tina B. Fontenot3 and Helen W. Lane2

1 Life Sciences Research Laboratories and
2 Medical Sciences Division, NASA Johnson Space Center, Houston, TX 77058.

3 KRUG Life Sciences, Houston, TX 77058.
a Address correspondence to this author at: Nutritional Biochemistry Laboratory, Life Sciences Research Laboratories, Mail Code SD3, NASA Johnson Space Center, Houston, TX 77058. Fax 281-483-2888; e-mail scott.m.smith1{at}jsc.nasa.gov

This study was designed to validate the utility of a commercial portable clinical blood analyzer (PCBA) in ground-based studies and on the space shuttle. Ionized calcium, pH, electrolytes, glucose, and hematocrit were determined. Results agreed well with those from traditional laboratory methods, and the PCBA demonstrated good between-day precision for all analytes. In-flight analysis of control samples revealed differences in one analyte (sodium). There were few changes in crew members' results during flight, and these were expected. Potassium increased in flight compared with before flight, and potassium, pH, and hematocrit decreased after flight. Ionized calcium was decreased in flight and on landing day. Changes during flight were likely related to sample collection technique. Postflight changes likely reflected the fluid redistribution that occurs after exposure to weightlessness. These data confirm that the PCBA is a reliable instrument for most analytes, and can provide important medical data in remote locations, such as orbiting spacecraft.


Key Words: indexing terms: point-of-care testing • electrolytes • ionized calcium • pH • biosensors




The following articles in journals at HighWire Press have cited this article:


Home page
 J. Nutr.Home page
S. M. Smith, S. A. Mathews Oliver, S. R. Zwart, G. Kala, P. A. Kelly, J. S. Goodwin, and C. B. Dyer
Nutritional Status Is Altered in the Self-Neglecting Elderly
J. Nutr., October 1, 2006; 136(10): 2534 - 2541.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
S. M. Smith, J. E. Davis-Street, J. V. Fesperman, M. D. Smith, B. L. Rice, and S. R. Zwart
Nutritional Status Changes in Humans during a 14-Day Saturation Dive: The NASA Extreme Environment Mission Operations V Project
J. Nutr., July 1, 2004; 134(7): 1765 - 1771.
[Abstract] [Full Text]

Home page
 Clin. Chem.Home page
M. D. Smith, J. E. Davis-Street, D. S. Calkins, J. L. Nillen, and S. M. Smith
Stability of i-Stat EC6+ Cartridges: Effect of Storage Temperature on Shelf Life
Clin. Chem., March 1, 2004; 50(3): 669 - 673.
[Full Text] [PDF]

Home page
 Clin. Chem.Home page
A. C. Gruszecki, G. Hortin, J. Lam, D. Kahler, D. Smith, J. Vines, L. Lancaster, T. M. Daly, C. A. Robinson, and R. W. Hardy
Utilization, Reliability, and Clinical Impact of Point-of-Care Testing during Critical Care Transport: Six Years of Experience
Clin. Chem., June 1, 2003; 49(6): 1017 - 1019.
[Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
S. M. Smith, M. E. Wastney, B. V. Morukov, I. M. Larina, L. E. Nyquist, S. A. Abrams, E. N. Taran, C.-Y. Shih, J. L. Nillen, J. E. Davis-Street, et al.
Calcium metabolism before, during, and after a 3-mo spaceflight: kinetic and biochemical changes
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 1999; 277(1): R1 - R10.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1997 by the American Association for Clinical Chemistry.