Clinical Chemistry
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Clinical Chemistry 43: 1500-1506, 1997;
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(Clinical Chemistry. 1997;43:1500-1506.)
© 1997 American Association for Clinical Chemistry, Inc.

Articles

Hepatitis B: diagnosis, prevention, and treatment

Norman Gitlin

Division of Digestive Diseases, Emory University School of Medicine, 2101 WMB, Atlanta, GA 30322. Fax 404-778-4715.

Hepatitis B virus (HBV) infection occurs worldwide and is an important cause of acute and chronic viral hepatitis in the US. In this review, I describe the virus, risk factors for infection, clinical features of infection, results of laboratory tests during infection, and standard and emerging treatment for chronic infection. Although 95% of adult patients recover completely from HBV infection, 90% of children <=4 years of age develop chronic infection. Active vaccination is highly efficacious.


Key Words: indexing terms: chronic disease • DNA virus • risk factors




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Performance of a New-Generation Chemiluminescent Assay for Hepatitis B Surface Antigen
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Rate of Hepatitis B Virus Infection in Pregnant Women Determined by a Monoclonal Hepatitis B Surface Antigen Immunoassay
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D. R. Dufour, J. A. Lott, F. S. Nolte, D. R. Gretch, R. S. Koff, and L. B. Seeff
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S. K. N. Ho, T. M. Chan, I. K. P. Cheng, and K. N. Lai
Comparison of the Second-Generation Digene Hybrid Capture Assay with the Branched-DNA Assay for Measurement of Hepatitis B Virus DNA in Serum
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V. C. H. Lai, R. Guan, M. L. Wood, S. K. Lo, M.-F. Yuen, and C.-L. Lai
Nucleic Acid-Based Cross-Linking Assay for Detection and Quantification of Hepatitis B Virus DNA
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