Clinical Chemistry Siemens Point of Care - Urinalysis
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 43: 1512-1526, 1997;
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (21)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sturgill, M. G.
Right arrow Articles by Lambert, G. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sturgill, M. G.
Right arrow Articles by Lambert, G. H.
Related Collections
Right arrow Arnold O. Beckman Conference
Right arrow Drug Monitoring and Toxicology
(Clinical Chemistry. 1997;43:1512-1526.)
© 1997 American Association for Clinical Chemistry, Inc.

Articles

Xenobiotic-induced hepatotoxicity: mechanisms of liver injury and methods of monitoring hepatic function

Marc G. Sturgill1,2 and George H. Lambert2,a

1 Department of Pharmacy Practice and Administration, Rutgers University College of Pharmacy, PO Box 789 William Levine Hall, Piscataway, NJ 08855-0789.

2 Division of Pediatric Pharmacology and Toxicology, University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School, 681 Frelinghuysen Rd., PO Box 1179, Piscataway, NJ 08855-1179.
a Author for correspondence. Fax (908) 281-0706; e-mail glambert{at}umdnj.edu

Xenobiotic-induced liver injury is a clinically important etiology of hepatic disease that, if not recognized, can lead to hepatic failure. In this article we discuss the mechanisms of xenobiotic-induced liver injury, various factors that can alter the risk and severity of injury, the clinical and laboratory manifestations of injury, and the methods used to detect the presence of injury and (or) functioning liver mass.


Key Words: indexing terms: xenobiotic metabolism • cytochrome P450 enzymes • cytotoxic/cholestatic liver injury • liver function tests




The following articles in journals at HighWire Press have cited this article:


Home page
 The Annals of PharmacotherapyHome page
K. P DeSanty and C. M Amabile
Antidepressant-Induced Liver Injury
Ann. Pharmacother., July 1, 2007; 41(7): 1201 - 1211.
[Abstract] [Full Text] [PDF]

Home page
 The Annals of PharmacotherapyHome page
R. Shakya, B S. Rao, and B. Shrestha
Incidence of Hepatotoxicity Due to Antitubercular Medicines and Assessment of Risk Factors
Ann. Pharmacother., June 1, 2004; 38(6): 1074 - 1079.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
A. B. Duguay, I. M. Yousef, and G. L. Plaa
Manganese-Bilirubin Effect on Cholesterol Accumulation in Rat Bile Canalicular Membranes
Toxicol. Sci., January 1, 2000; 53(1): 150 - 155.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1997 by the American Association for Clinical Chemistry.