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Clinical Chemistry 43: 1527-1534, 1997;
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(Clinical Chemistry. 1997;43:1527-1534.)
© 1997 American Association for Clinical Chemistry, Inc.

Articles

Fatty acid ethyl esters: short-term and long-term serum markers of ethanol intake

Michael Laposataa

a Address for correspondence: Room 235, Gray Bldg., Massachusetts General Hospital, Fruit St., Boston, MA 02114. Fax 617-726-3256; e-mail LAPOSATAMI{at}A1.mgh.harvard.edu

This review includes a description of short-term and long-term markers of ethanol intake and their clinical utility. The major portion of this report is a summary of studies on fatty acid ethyl ester, a new marker for monitoring both acute and chronic ethanol intake. With the markers described in the review, algorithms to assess recent ethanol intake, chronic ethanol intake, and end organ damage are included to provide a practical approach to the evaluation of the patient.


Key Words: indexing terms: alcohol • fatty acids • lipids • pancreatic disorders • liver disorders • cirrhosis • alcoholism • ethanol abuse • addiction




The following articles in journals at HighWire Press have cited this article:


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M. CECCANTI, R. MANCINELLI, G. F. SASSO, J. P. ALLEN, R. BINETTI, A. MELLINI, F. ATTILIA, L. TOPPO, and M. L. ATTILIA
ERYTHROCYTE THIAMINE (Th) ESTERS: A MAJOR FACTOR OF THE ALCOHOL WITHDRAWAL SYNDROME OR A CANDIDATE MARKER FOR ALCOHOLISM ITSELF?
Alcohol Alcohol., July 1, 2005; 40(4): 283 - 290.
[Abstract] [Full Text] [PDF]

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A. BISAGA, M. LAPOSATA, S. XIE, and S. M. EVANS
COMPARISON OF SERUM FATTY ACID ETHYL ESTERS AND URINARY 5-HYDROXYTRYPTOPHOL AS BIOCHEMICAL MARKERS OF RECENT ETHANOL CONSUMPTION
Alcohol Alcohol., May 1, 2005; 40(3): 214 - 218.
[Abstract] [Full Text] [PDF]

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C. Derauf, A. R. Katz, and D. Easa
Agreement between Maternal Self-reported Ethanol Intake and Tobacco Use During Pregnancy and Meconium Assays for Fatty Acid Ethyl Esters and Cotinine
Am. J. Epidemiol., October 1, 2003; 158(7): 705 - 709.
[Abstract] [Full Text] [PDF]

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S. Hartwig, V. Auwarter, and F. Pragst
FATTY ACID ETHYL ESTERS IN SCALP, PUBIC, AXILLARY, BEARD AND BODY HAIR AS MARKERS FOR ALCOHOL MISUSE
Alcohol Alcohol., March 1, 2003; 38(2): 163 - 167.
[Abstract] [Full Text] [PDF]

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V. Auwarter, F. Sporkert, S. Hartwig, F. Pragst, H. Vater, and A. Diefenbacher
Fatty Acid Ethyl Esters in Hair as Markers of Alcohol Consumption. Segmental Hair Analysis of Alcoholics, Social Drinkers, and Teetotalers
Clin. Chem., December 1, 2001; 47(12): 2114 - 2123.
[Abstract] [Full Text] [PDF]

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W. C. Zybko, J. E. Cluette-Brown, and M. Laposata
Improved Sensitivity and Reduced Sample Size in Serum Fatty Acid Ethyl Ester Analysis
Clin. Chem., June 1, 2001; 47(6): 1120 - 1121.
[Full Text] [PDF]

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R. O. Salem, J. E. Cluette-Brown, A. Hasaba, and M. Laposata
Effect of Specimen Anticoagulant and Storage on Measurement of Serum and Plasma Fatty Acid Ethyl Ester Concentrations.
Clin. Chem., January 1, 2001; 47(1): 126 - 127.
[Full Text] [PDF]


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Copyright © 1997 by the American Association for Clinical Chemistry.