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Clinical Chemistry 44: 1821-1825, 1998;
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(Clinical Chemistry. 1998;44:1821-1825.)
© 1998 American Association for Clinical Chemistry, Inc.


Proceedings of the 21st Arnold O. Beckman Conference

Obesity and cardiovascular disease

James R. Sowers

Department of Internal Medicine, Wayne State University School of Medicine, 4201 St. Antoine, UHC-4H, Detroit, MI 48201. Fax 313-993-0903; e-mail sowers{at}oncgate.roc.wayne.edu.


Abstract

Obesity, diabetes mellitus, and hypertension are common, interrelated medical problems in Westernized, industrialized societies. These interrelated medical conditions are associated with an increased risk of cardiovascular disease and are more prevalent in several minority groups, including African-American and Hispanic populations. The associated cardiovascular risks of these problems are more thoroughly addressed in another review in this supplement. Obesity markedly enhances the development of Type 2 diabetes. Moreover, it enhances the cardiovascular risk associated with other risk factors, such as hypertension and dyslipidemia. Weight reduction in association with an aerobic exercise program improves metabolic abnormalities and reduces blood pressure in individuals with diabetes and hypertension.




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