Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 45: 7-17, 1999;
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (302)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chen, F.
Right arrow Articles by Demers, L. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chen, F.
Right arrow Articles by Demers, L. M.
Related Collections
Right arrow Molecular Diagnostics and Genetics
Right arrow Endocrinology and Metabolism
(Clinical Chemistry. 1999;45:7-17.)
© 1999 American Association for Clinical Chemistry, Inc.

Review

New Insights into the Role of Nuclear Factor-{kappa}B, a Ubiquitous Transcription Factor in the Initiation of Diseases

Fei Chen1,2,a, Vince Castranova1, Xianglin Shi1 and Laurence M. Demers2

1 Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505.

2 Department of Pathology, The Pennsylvania State University College of Medicine, Hershey, PA 17033.
a Author for correspondence. Fax (304) 285-5938; e-mail lfd3{at}cdc.gov.

Nuclear factor-{kappa}B (NF-{kappa}B) is a ubiquitous transcription factor that governs the expression of genes encoding cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NF-{kappa}B is activated by several agents, including cytokines, oxidant free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-{kappa}B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-{kappa}B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. Therefore, development of modulatory strategies targeting this transcription factor may provide a novel therapeutic tool for the treatment or prevention of various diseases.




The following articles in journals at HighWire Press have cited this article:


Home page
 Ann OncolHome page
B. Zhou, M. Qie, Y. Wang, L. Yan, Z. Zhang, A. Liang, T. Wang, X. Wang, Y. Song, and L. Zhang
Relationship between NFKB1 -94 insertion/deletion ATTG polymorphism and susceptibility of cervical squamous cell carcinoma risk
Ann. Onc., November 5, 2009; (2009) mdp507v1.
[Abstract] [Full Text] [PDF]

Home page
 Jpn J Clin OncolHome page
J. G. Kim, S. K. Sohn, Y. S. Chae, J. H. Moon, S. N. Kim, B. W. Kang, G. C. Kim, M.-H. Lee, S. W. Jeon, H. Y. Chung, et al.
No Association of the NFKB1 Insertion/Deletion Promoter Polymorphism with Survival in Patients with Gastric Cancer
Jpn. J. Clin. Oncol., August 1, 2009; 39(8): 497 - 501.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
S. Gupta, R. Maitra, D. Young, A. Gupta, and S. Sen
Silencing the myotrophin gene by RNA interference leads to the regression of cardiac hypertrophy
Am J Physiol Heart Circ Physiol, August 1, 2009; 297(2): H627 - H636.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
J. Yang, M. F. Siqueira, Y. Behl, M. Alikhani, and D. T. Graves
The transcription factor ST18 regulates proapoptotic and proinflammatory gene expression in fibroblasts
FASEB J, November 1, 2008; 22(11): 3956 - 3967.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
Z. Zhou, P. Gengaro, W. Wang, X.-q. Wang, C. Li, S. Faubel, C. Rivard, and R. W. Schrier
Role of NF-{kappa}B and PI 3-kinase/Akt in TNF-{alpha}-induced cytotoxicity in microvascular endothelial cells
Am J Physiol Renal Physiol, October 1, 2008; 295(4): F932 - F941.
[Abstract] [Full Text] [PDF]

Home page
 CarcinogenesisHome page
E. I. Ager, J. Neo, and C. Christophi
The renin-angiotensin system and malignancy
Carcinogenesis, September 1, 2008; 29(9): 1675 - 1684.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J.-P. Lai, S. Lai, F. Tuluc, M. F. Tansky, L. E. Kilpatrick, S. E. Leeman, and S. D. Douglas
Differences in the length of the carboxyl terminus mediate functional properties of neurokinin-1 receptor
PNAS, August 26, 2008; 105(34): 12605 - 12610.
[Abstract] [Full Text] [PDF]

Home page
 Annals of Clinical & Laboratory ScienceHome page
W. Jin, L. Zhu, Q. Guan, G. Chen, Q. F. Wang, H. X. Yin, C. H. Hang, J. X. Shi, and H. D. Wang
Influence of Nrf2 Genotype on Pulmonary NF-{kappa}B Activity and Inflammatory Response after Traumatic Brain Injury
Ann. Clin. Lab. Sci., January 1, 2008; 38(3): 221 - 227.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
H. Fujimoto, C. N. D'Alessandro-Gabazza, M. S. S. Palanki, P. E. Erdman, T. Takagi, E. C. Gabazza, N. E. Bruno, Y. Yano, T. Hayashi, S. Tamaki, et al.
Inhibition of Nuclear Factor-{kappa}B in T Cells Suppresses Lung Fibrosis
Am. J. Respir. Crit. Care Med., December 15, 2007; 176(12): 1251 - 1260.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
S. J. Chapman, C. C. Khor, F. O. Vannberg, A. Frodsham, A. Walley, N. A. Maskell, C. W. H. Davies, S. Segal, C. E. Moore, S. H. Gillespie, et al.
I{kappa}B Genetic Polymorphisms and Invasive Pneumococcal Disease
Am. J. Respir. Crit. Care Med., July 15, 2007; 176(2): 181 - 187.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
O. L. Volger, J. O. Fledderus, N. Kisters, R. D. Fontijn, P. D. Moerland, J. Kuiper, T. J. van Berkel, A.-P. J.J. Bijnens, M. J.A.P. Daemen, H. Pannekoek, et al.
Distinctive Expression of Chemokines and Transforming Growth Factor-{beta} Signaling in Human Arterial Endothelium during Atherosclerosis
Am. J. Pathol., July 1, 2007; 171(1): 326 - 337.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
M. C. Carreras and J. J. Poderoso
Mitochondrial nitric oxide in the signaling of cell integrated responses
Am J Physiol Cell Physiol, May 1, 2007; 292(5): C1569 - C1580.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
A. M. Miller, M. J. Nolan, J. Choi, T. Koga, X. Shen, B. Y. J. T. Yue, and P. A. Knepper
Lactate Treatment Causes NF-{kappa}B Activation and CD44 Shedding in Cultured Trabecular Meshwork Cells
Invest. Ophthalmol. Vis. Sci., April 1, 2007; 48(4): 1615 - 1621.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Kaileh, W. Vanden Berghe, A. Heyerick, J. Horion, J. Piette, C. Libert, D. De Keukeleire, T. Essawi, and G. Haegeman
Withaferin A Strongly Elicits I{kappa}B Kinase beta Hyperphosphorylation Concomitant with Potent Inhibition of Its Kinase Activity
J. Biol. Chem., February 16, 2007; 282(7): 4253 - 4264.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
W. Boonyasrisawat, D. Eberle, S. Bacci, Y.-Y. Zhang, D. Nolan, E. V. Gervino, M. T. Johnstone, V. Trischitta, S. E. Shoelson, and A. Doria
Tag Polymorphisms at the A20 (TNFAIP3) Locus Are Associated With Lower Gene Expression and Increased Risk of Coronary Artery Disease in Type 2 Diabetes
Diabetes, February 1, 2007; 56(2): 499 - 505.
[Abstract] [Full Text] [PDF]

Home page
 Mol Cancer ResHome page
Y. Yan, Y. Lu, M. Wang, H. Vikis, R. Yao, Y. Wang, R. A. Lubet, and M. You
Effect of an Epidermal Growth Factor Receptor Inhibitor in Mouse Models of Lung Cancer
Mol. Cancer Res., December 1, 2006; 4(12): 971 - 981.
[Abstract] [Full Text] [PDF]

Home page
 Integr. Comp. Biol.Home page
A. Heyland and L. L. Moroz
Signaling mechanisms underlying metamorphic transitions in animals
Integr. Comp. Biol., December 1, 2006; 46(6): 743 - 759.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
F. Chen, Y. Lu, V. Castranova, Z. Li, and M. Karin
Loss of Ikkbeta Promotes Migration and Proliferation of Mouse Embryo Fibroblast Cells
J. Biol. Chem., December 1, 2006; 281(48): 37142 - 37149.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
S. Xu, H. Bayat, X. Hou, and B. Jiang
Ribosomal S6 kinase-1 modulates interleukin-1beta-induced persistent activation of NF-{kappa}B through phosphorylation of I{kappa}Bbeta
Am J Physiol Cell Physiol, December 1, 2006; 291(6): C1336 - C1345.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
X. Zhou, W. Yang, and J. Li
Ca2+- and Protein Kinase C-dependent Signaling Pathway for Nuclear Factor-{kappa}B Activation, Inducible Nitric-oxide Synthase Expression, and Tumor Necrosis Factor-{alpha} Production in Lipopolysaccharide-stimulated Rat Peritoneal Macrophages
J. Biol. Chem., October 20, 2006; 281(42): 31337 - 31347.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
V. Liebe, M. Brueckmann, M. Borggrefe, and J. J. Kaden
Statin therapy of calcific aortic stenosis: hype or hope?
Eur. Heart J., April 1, 2006; 27(7): 773 - 778.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
J. L. Kang, H. J. Jung, K. Lee, and H. R. Kim
Src Tyrosine Kinases Mediate Crystalline Silica-Induced NF-{kappa}B Activation through Tyrosine Phosphorylation of I{kappa}B-{alpha} and p65 NF-{kappa}B in RAW 264.7 Macrophages
Toxicol. Sci., April 1, 2006; 90(2): 470 - 477.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
C.-H. Yang, I-M. Fang, C.-P. Lin, C.-M. Yang, and M.-S. Chen
Effects of the NF-{kappa}B Inhibitor Pyrrolidine Dithiocarbamate on Experimentally Induced Autoimmune Anterior Uveitis
Invest. Ophthalmol. Vis. Sci., April 1, 2005; 46(4): 1339 - 1347.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
S. Lee and C. Rivier
Role Played by Hypothalamic Nuclear Factor-{kappa}B in Alcohol-Mediated Activation of the Rat Hypothalamic-Pituitary-Adrenal Axis
Endocrinology, April 1, 2005; 146(4): 2006 - 2014.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
N. Franscini, E. B. Bachli, N. Blau, M.-S. Leikauf, A. Schaffner, and G. Schoedon
Gene Expression Profiling of Inflamed Human Endothelial Cells and Influence of Activated Protein C
Circulation, November 2, 2004; 110(18): 2903 - 2909.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
F. J. Dieguez-Acuna, W. W. Polk, M. E. Ellis, P. L. Simmonds, J. V. Kushleika, and J. S. Woods
Nuclear Factor {kappa}B Activity Determines the Sensitivity of Kidney Epithelial Cells to Apoptosis: Implications for Mercury-Induced Renal Failure
Toxicol. Sci., November 1, 2004; 82(1): 114 - 123.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
L. S. Adams and D. Teegarden
1,25-Dihydroxycholecalciferol Inhibits Apoptosis in C3H10T1/2 Murine Fibroblast Cells Through Activation of Nuclear Factor {kappa}B
J. Nutr., November 1, 2004; 134(11): 2948 - 2952.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
S.-J. Jeong, M. Radonovich, J. N. Brady, and C. A. Pise-Masison
HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity
Blood, September 1, 2004; 104(5): 1490 - 1497.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
S. Guerra, L. A. Lopez-Fernandez, R. Conde, A. Pascual-Montano, K. Harshman, and M. Esteban
Microarray Analysis Reveals Characteristic Changes of Host Cell Gene Expression in Response to Attenuated Modified Vaccinia Virus Ankara Infection of Human HeLa Cells
J. Virol., June 1, 2004; 78(11): 5820 - 5834.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
B. Jiang, S. Xu, X. Hou, D. R. Pimentel, and R. A. Cohen
Angiotensin II Differentially Regulates Interleukin-1-{beta}-inducible NO Synthase (iNOS) and Vascular Cell Adhesion Molecule-1 (VCAM-1) Expression: ROLE OF p38 MAPK
J. Biol. Chem., May 7, 2004; 279(19): 20363 - 20368.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. A. McCracken, E. Gallery, and J. M. Morris
Pregnancy-Specific Down-Regulation of NF-{kappa}B Expression in T Cells in Humans Is Essential for the Maintenance of the Cytokine Profile Required for Pregnancy Success
J. Immunol., April 1, 2004; 172(7): 4583 - 4591.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
T. Y. Ma, G. K. Iwamoto, N. T. Hoa, V. Akotia, A. Pedram, M. A. Boivin, and H. M. Said
TNF-{alpha}-induced increase in intestinal epithelial tight junction permeability requires NF-{kappa}B activation
Am J Physiol Gastrointest Liver Physiol, March 1, 2004; 286(3): G367 - G376.
[Abstract] [Full Text] [PDF]

Home page
 J. Am. Coll. Nutr.Home page
Y. Zhao, S. Joshi-Barve, S. Barve, and L. H. Chen
Eicosapentaenoic Acid Prevents LPS-Induced TNF-{alpha} Expression by Preventing NF-{kappa}B Activation
J. Am. Coll. Nutr., February 1, 2004; 23(1): 71 - 78.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
E. Hagi-Pavli, P. M. Farthing, and S. Kapas
Stimulation of adhesion molecule expression in human endothelial cells (HUVEC) by adrenomedullin and corticotrophin
Am J Physiol Cell Physiol, February 1, 2004; 286(2): C239 - C246.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
B. Jiang, S. Xu, X. Hou, D. R. Pimentel, P. Brecher, and R. A. Cohen
Temporal Control of NF-{kappa}B Activation by ERK Differentially Regulates Interleukin-1{beta}-induced Gene Expression
J. Biol. Chem., January 9, 2004; 279(2): 1323 - 1329.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
A. S. Karban, T. Okazaki, C. I.M. Panhuysen, T. Gallegos, J. J. Potter, J. E. Bailey-Wilson, M. S. Silverberg, R. H. Duerr, J. H. Cho, P. K. Gregersen, et al.
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis
Hum. Mol. Genet., January 1, 2004; 13(1): 35 - 45.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
K. Yamamoto, T. Shioi, K. Uchiyama, T. Miyamoto, S. Sasayama, and A. Matsumori
Attenuation of virus-induced myocardial injury by inhibition of the angiotensin II type 1 receptor signal and decreased nuclear factor-kappa B activation in knockout mice
J. Am. Coll. Cardiol., December 3, 2003; 42(11): 2000 - 2006.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
F. Lebron, R. Vassallo, V. Puri, and A. H. Limper
Pneumocystis carinii Cell Wall {beta}-Glucans Initiate Macrophage Inflammatory Responses through NF-{kappa}B Activation
J. Biol. Chem., June 27, 2003; 278(27): 25001 - 25008.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. E. Poynter, C. G. Irvin, and Y. M. W. Janssen-Heininger
A Prominent Role for Airway Epithelial NF-{kappa}B Activation in Lipopolysaccharide-Induced Airway Inflammation
J. Immunol., June 15, 2003; 170(12): 6257 - 6265.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
G. Alexander, H. Carlsen, and R. Blomhoff
Strong In Vivo Activation of NF-{kappa}B in Mouse Lenses by Classic Stressors
Invest. Ophthalmol. Vis. Sci., June 1, 2003; 44(6): 2683 - 2688.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
S. Gupta, N. H. Purcell, A. Lin, and S. Sen
Activation of nuclear factor-{kappa}B is necessary for myotrophin-induced cardiac hypertrophy
J. Cell Biol., December 23, 2002; 159(6): 1019 - 1028.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
B. Jiang, S. Xu, P. Brecher, and R. A. Cohen
Growth Factors Enhance Interleukin-1{beta}-Induced Persistent Activation of Nuclear Factor-{kappa}B in Rat Vascular Smooth Muscle Cells
Arterioscler Thromb Vasc Biol, November 1, 2002; 22(11): 1811 - 1816.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
P. Cameron, D. Bingham, A. Paul, M. Pavelka, S. Cameron, D. Rotondo, and R. Plevin
Essential Role for Verotoxin in Sustained Stress-Activated Protein Kinase and Nuclear Factor Kappa B Signaling, Stimulated by Escherichia coli O157:H7 in Vero Cells
Infect. Immun., October 1, 2002; 70(10): 5370 - 5380.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
O. Lopez-Franco, Y. Suzuki, G. Sanjuan, J. Blanco, P. Hernandez-Vargas, Y. Yo, J. Kopp, J. Egido, and C. Gomez-Guerrero
Nuclear Factor-{kappa}B Inhibitors as Potential Novel Anti-Inflammatory Agents for the Treatment of Immune Glomerulonephritis
Am. J. Pathol., October 1, 2002; 161(4): 1497 - 1505.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
M. T Gewaltig and G. Kojda
Vasoprotection by nitric oxide: mechanisms and therapeutic potential
Cardiovasc Res, August 1, 2002; 55(2): 250 - 260.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
M. P. Russo, B. L. Bennett, A. M. Manning, D. A. Brenner, and C. Jobin
Differential requirement for NF-kappa B-inducing kinase in the induction of NF-kappa B by IL-1beta , TNF-alpha , and Fas
Am J Physiol Cell Physiol, July 1, 2002; 283(1): C347 - C357.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D.-w. Jeong, M.-H. Yoo, T. S. Kim, J.-H. Kim, and I. Y. Kim
Protection of Mice from Allergen-induced Asthma by Selenite. PREVENTION OF EOSINOPHIL INFILTRATION BY INHIBITION OF NF-kappa B ACTIVATION
J. Biol. Chem., May 10, 2002; 277(20): 17871 - 17876.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
Y. K. Gruijthuijsen, P. Casarosa, S. J. F. Kaptein, J. L. V. Broers, R. Leurs, C. A. Bruggeman, M. J. Smit, and C. Vink
The Rat Cytomegalovirus R33-Encoded G Protein-Coupled Receptor Signals in a Constitutive Fashion
J. Virol., February 1, 2002; 76(3): 1328 - 1338.
[Abstract] [Full Text] [PDF]

Home page
 Vet PatholHome page
E. W. Uhl, S. Giguere, T. J. Jack, and T. Hodge
Increased Pulmonary Activation of Nuclear Factor-{kappa}B (NF-{kappa}B) in Foals Inoculated with Rhodococcus equi is Associated with Increased Expression of Inflammatory Cytokines
Vet. Pathol., January 1, 2002; 39(1): 132 - 136.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
B. Jiang, P. Brecher, and R. A. Cohen
Persistent Activation of Nuclear Factor-{kappa}B by Interleukin-1{beta} and Subsequent Inducible NO Synthase Expression Requires Extracellular Signal-Regulated Kinase
Arterioscler Thromb Vasc Biol, December 1, 2001; 21(12): 1915 - 1920.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
G. Valen, Z.-q. Yan, and G.o. K. Hansson
Nuclear factor kappa-B and the heart
J. Am. Coll. Cardiol., August 1, 2001; 38(2): 307 - 314.
[Abstract] [Full Text] [PDF]

Home page
 J. Am. Soc. Nephrol.Home page
G. K. RANGAN, Y. WANG, and D. C. H. HARRIS
Pharmacologic Modulators of Nitric Oxide Exacerbate Tubulointerstitial Inflammation in Proteinuric Rats
J. Am. Soc. Nephrol., August 1, 2001; 12(8): 1696 - 1705.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
F. Chen, V. Castranova, and X. Shi
New Insights into the Role of Nuclear Factor-{kappa}B in Cell Growth Regulation
Am. J. Pathol., August 1, 2001; 159(2): 387 - 397.
[Abstract] [Full Text]

Home page
 J. Immunol.Home page
C. M. Fleming, H. He, A. Ciota, D. Perkins, and P. W. Finn
Administration of Pentoxifylline During Allergen Sensitization Dissociates Pulmonary Allergic Inflammation from Airway Hyperresponsiveness
J. Immunol., August 1, 2001; 167(3): 1703 - 1711.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
M. Adib-Conquy, K. Asehnoune, P. Moine, and J.-M. Cavaillon
Long-term-impaired expression of nuclear factor-{kappa}B and I{kappa}B{alpha} in peripheral blood mononuclear cells of trauma patients
J. Leukoc. Biol., July 1, 2001; 70(1): 30 - 38.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
M. Ruiz-Ortega, O. Lorenzo, M. Ruperez, J. Blanco, and J. Egido
Systemic Infusion of Angiotensin II into Normal Rats Activates Nuclear Factor-{{kappa}}B and AP-1 in the Kidney : Role of AT1 and AT2 Receptors
Am. J. Pathol., May 1, 2001; 158(5): 1743 - 1756.
[Abstract] [Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
E. Ho, N. Quan, Y.-H. Tsai, W. Lai, and T. M. Bray
Dietary Zinc Supplementation Inhibits NF {{kappa}}B Activation and Protects Against Chemically Induced Diabetes in CD1 Mice
Experimental Biology and Medicine, February 1, 2001; 226(2): 103 - 111.
[Abstract] [Full Text]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
H.-M. Shen, Z. Zhang, Q.-F. Zhang, and C.-N. Ong
Reactive oxygen species and caspase activation mediate silica-induced apoptosis in alveolar macrophages
Am J Physiol Lung Cell Mol Physiol, January 1, 2001; 280(1): L10 - L17.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
Y.-H. Li, Z.-Q. Yan, J. S. Jensen, K. Tullus, and A. Brauner
Activation of Nuclear Factor kappa B and Induction of Inducible Nitric Oxide Synthase by Ureaplasma urealyticum in Macrophages
Infect. Immun., December 1, 2000; 68(12): 7087 - 7093.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
T. A. Blinman, I. Gukovsky, M. Mouria, V. Zaninovic, E. Livingston, S. J. Pandol, and A. S. Gukovskaya
Activation of pancreatic acinar cells on isolation from tissue: cytokine upregulation via p38 MAP kinase
Am J Physiol Cell Physiol, December 1, 2000; 279(6): C1993 - C2003.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
F. Chen, L. M. Demers, V. Vallyathan, Y. Lu, V. Castranova, and X. Shi
Impairment of NF-kappa B activation and modulation of gene expression by calpastatin
Am J Physiol Cell Physiol, September 1, 2000; 279(3): C709 - C716.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
M. D. S. Jean, C. Debbasch, M. Rahmani, F. Brignole, G. Feldmann, J.-M. Warnet, and C. Baudouin
Fas- and Interferon {gamma}-Induced Apoptosis in Chang Conjunctival Cells: Further Investigations
Invest. Ophthalmol. Vis. Sci., August 1, 2000; 41(9): 2531 - 2543.
[Abstract] [Full Text]

Home page
 J. Immunol.Home page
E. R. Fields, B. J. Seufzer, E. M. Oltz, and S. Miyamoto
A Switch in Distinct I{kappa}B{alpha} Degradation Mechanisms Mediates Constitutive NF-{kappa}B Activation in Mature B Cells
J. Immunol., May 1, 2000; 164(9): 4762 - 4767.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
F. Arnalich, E. Garcia-Palomero, J. Lopez, M. Jimenez, R. Madero, J. Renart, J. J. Vazquez, and C. Montiel
Predictive Value of Nuclear Factor kappa B Activity and Plasma Cytokine Levels in Patients with Sepsis
Infect. Immun., April 1, 2000; 68(4): 1942 - 1945.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
M. F. Romano, A. Lamberti, R. Bisogni, C. Garbi, A. M. Pagnano, P. Auletta, P. Tassone, M. C. Turco, and S. Venuta
Amifostine Inhibits Hematopoietic Progenitor Cell Apoptosis by Activating NF-kappa B/Rel Transcription Factors
Blood, December 15, 1999; 94(12): 4060 - 4066.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
F. Chen, L. M. Demers, V. Vallyathan, Y. Lu, V. Castranova, and X. Shi
Involvement of 5'-Flanking kappa B-like Sites within bcl-x Gene in Silica-induced Bcl-x Expression
J. Biol. Chem., December 10, 1999; 274(50): 35591 - 35595.
[Abstract] [Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
E. Ho and T. M. Bray
Antioxidants, NF{kappa}B Activation, and Diabetogenesis
Experimental Biology and Medicine, December 1, 1999; 222(3): 205 - 213.
[Abstract] [Full Text]

Home page
 Am. J. Pathol.Home page
F. Chen, Y. Lu, V. Castranova, Y. Rojanasakul, K. Miyahara, Y. Shizuta, V. Vallyathan, X. Shi, and L. M. Demers
Nitric Oxide Inhibits HIV Tat-Induced NF-{kappa}B Activation
Am. J. Pathol., July 1, 1999; 155(1): 275 - 284.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. W. Anthonsen, A. Solhaug, and B. Johansen
Functional Coupling between Secretory and Cytosolic Phospholipase A2 Modulates Tumor Necrosis Factor-alpha - and Interleukin-1beta -induced NF-kappa B Activation
J. Biol. Chem., August 3, 2001; 276(32): 30527 - 30536.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Casarosa, R. A. Bakker, D. Verzijl, M. Navis, H. Timmerman, R. Leurs, and M. J. Smit
Constitutive Signaling of the Human Cytomegalovirus-encoded Chemokine Receptor US28
J. Biol. Chem., January 5, 2001; 276(2): 1133 - 1137.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
F. Chen, Y. Lu, Z. Zhang, V. Vallyathan, M. Ding, V. Castranova, and X. Shi
Opposite Effect of NF-kappa B and c-Jun N-terminal Kinase on p53-independent GADD45 Induction by Arsenite
J. Biol. Chem., March 30, 2001; 276(14): 11414 - 11419.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Van Huffel, F. Delaei, K. Heyninck, D. De Valck, and R. Beyaert
Identification of a Novel A20-binding Inhibitor of Nuclear Factor-kappa B Activation Termed ABIN-2
J. Biol. Chem., August 3, 2001; 276(32): 30216 - 30223.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1999 by the American Association for Clinical Chemistry.